Nanofluids, the fluid suspensions of nanomaterials , have shown many interesting properties, and the distinctive feature offer unprecedented potential for many applications. Nanofluids which are known as new generation of thermal fluids have particular feature which are affected on their behavior. Present paper focuses on behavior of nanofluids in crystallization. The objectives of this paper are to visualize the effect of nanofluid in crystallization operation as compared to convectional fluids i.e water (DW). Results are presented in terms of heat transfer coefficient. For 1% nanofluid heat transfer coefficient is 255.645 w/m 2o K and 264.438 w/m 2o K for 3% nanofluids which enhance significantly the crystallization performance. The use of CuO nanofluids in crystallizer increases the yield of crystallizer. The percentage increase in yield for 1% nanofluids is 4.4% and for 3% nanofluids percentage increase in yield was 5.5%. The nanoparticles used in the experiment was 98.5% pure copper oxide, with an average particle size of 32 nm synthesized by using chemical precipitation method. The nanofluid was prepared by mixing nanoparticles with de-ionized water to prepare experimental concentration of 1% and 3%. The magnesium sulfate solution to be crystallizing is prepared in lab and the average percentage increases heat transfer coefficients for 1% nano-Fluid was found to be 13.1% and 22.31 for 3% nanofluids.