Prevalência de lesões cutâneas actínicas em pacientes com carcinoma basocelular do segmento cefálico: um estudo caso-controle

Chinem, Valquíria Pessoa; Miot, Hélio Amante

doi:10.1590/s0104-42302012000200014

Cited by 1 publication

(1 citation statement)

References 49 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Besides, lighter-skinned individuals who are at higher risk for actinic lesions, are also the most effective synthesizers of VD, what minimizes the impact of sunscreen in VD synthesis. 38,39…”

Section: Discussionmentioning

confidence: 99%

Evaluation of vitamin D plasma levels after mild exposure to the sun with photoprotection

Pereira

Luz

Carneiro

et al. 2019

An. Bras. Dermatol.

View full text Add to dashboard Cite

BackgroundMost of the organism’s vitamin D (VD) is obtained through the cutaneous synthesis after exposure to the sun’s UVB radiation. Sunscreens are indicated for the prevention of actinic damage to the skin, however, there are few clinical trials assessing the synthesis of cutaneous VD in real-life situations of sun exposure with ordinary clothing and usual photoprotection.ObjectivesTo evaluate the synthesis of VD with suberythemal sun exposure in healthy adults using topical photoprotection (SPF 30).MethodsQuasi-experimental study, conducted at Rio de Janeiro (Brazil), during winter, with 95 healthy adults who had 25-OH-VD checked twice, 24 hours apart, and were exposed to the sun (UVB=20 mJ/cm2), according to a randomized grouping: SC - use of SPF 30 on the face, neck and chest (n=64), NO - no sunscreens (n=10), CO - confined from sun exposure for 24h (n=21). The groups were matched according to the propensity score related to gender, age, phototype, body mass index, glycosylated hemoglobin and baseline levels of VD. The outcome evaluated was the variation (ΔVD) in serum level of 25-OH-VD (ng/ml) between the groups.ResultsA statistically significant difference was identified between CO and SC groups [median (p25-p75)]: ΔVD =1.4 (-0.3-3.6) vs. 5.5 (4.8-6.6); p<0.01. There was no difference between SC and NO groups: 5.4 (3.1-6.1) vs. 4.1 (2.5-6.0); p=0.17.Study limitationsLaboratory analysis technique (chemiluminescence) with great variability, loss of food intake standardatization, unbalanced groups.ConclusionsSuberythemal sun exposure with sunscreen (SPF 30) provides similar vitamin D serum variation than without photoprotection in healthy adults.

show abstract

Section: Discussionmentioning

confidence: 99%

Evaluation of vitamin D plasma levels after mild exposure to the sun with photoprotection

Pereira

Luz

Carneiro

et al. 2019

An. Bras. Dermatol.

View full text Add to dashboard Cite

show abstract

Prevalência de lesões cutâneas actínicas em pacientes com carcinoma basocelular do segmento cefálico: um estudo caso-controle

Abstract: Actinic lesions were more prevalent in patients with solid basal cell carcinoma of the head than in controls, especially milia, cutis rhomboidalis nuchae, and leukoderma punctata, regardless of other known risk factors.

Cited by 1 publication

References 49 publications

Evaluation of vitamin D plasma levels after mild exposure to the sun with photoprotection

Evaluation of vitamin D plasma levels after mild exposure to the sun with photoprotection

Contact Info

Product

Resources

About