"Pólipos da vesícula biliar: e quando tratar?"

Ilias, Elias Jirjoss

doi:10.1590/s0104-42302010000300001

Cited by 3 publications

(3 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[8] They are local epithelial proliferation inflammatory reactions with infiltration of inflammatory cells and are often associated with chronic cholecystitis. [132]…”

Section: Histopathologymentioning

confidence: 99%

See 1 more Smart Citation

Diagnosis and Management of Gallbladder Polyps

2012

View full text Add to dashboard Cite

Gallbladder cancer is a rather uncommon disease, when it gives symptoms it has usually reached an incurable stage. Therefore, every attempt must be made to find the asymptomatic stages and look for premalignant gallbladder polyps. Even if gallbladder cancer is a rare disease, gallbladder polyps are common, only a few polyps develop to cancer. This makes gallbladder polyps another problem: which are the polyps that must be surgically removed, which shall be followed-up, or for how long? The author used the keyword “gallbladder polypsn” in PubMed and reviewed the scientific literatures published from January 2000 to December 2011. The present review article has summarized almost all respects of gallbladder polyp, including the risk factors, clinical diagnosis and management, and comments made from the author, in which clinical treatments are recommended. It is author's purpose that the 11-year-knowledge about gallbladder polyps summarized from all worlds’ literatures is enough to know how clinicians will handle the next patient with gallbladder polyp.

show abstract

“…[8] They are local epithelial proliferation inflammatory reactions with infiltration of inflammatory cells and are often associated with chronic cholecystitis. [132]…”

Section: Histopathologymentioning

confidence: 99%

“…However, some studies have demonstrated that the polyp's diameter alone is not a safe exclusion criteria for neoplasm,[232] and therefore, recommend strongly consideration for cholecystectomy for any polyp greater than 6 mm. [937]…”

Section: Prediction Of Malignancymentioning

confidence: 99%

Diagnosis and Management of Gallbladder Polyps

2012

View full text Add to dashboard Cite

show abstract

“…And if the diameter has a discrepancy or only seen in the USG, the GB polyp can be considered as a cholesterol polyp and require planning for another follow-up after 6 months [29,30] thereby delaying the operation. We suggest that it would be more efficient to make flexible treatment plans for the mentioned cases rather than the fixed guideline.…”

Section: Discussionmentioning

confidence: 99%

Clinical and radiologic preoperative predicting factors for GB cholesterol polyp

et al. 2012

View full text Add to dashboard Cite

Purpose To use the clinical and radiological data to differentiate non-cholesterol versus cholesterol gall bladder (GB) polyps, which can be useful in deciding the treatment of the patient. Methods One hundred and eighty-seven patients underwent cholecystectomy for GB polyps of around 10 mm for 10 years, and were divided into two groups, cholesterol polyps (146 patients) and non-cholesterol polyps (41 patients) based on the postoperative pathological findings. Gender, age, body weight, height, body mass index (BMI), symptoms, laboratory findings, size, number of polyps, presence of GB stone and maximum diameter measured by preoperative ultrasonography (USG), computed tomography (CT), and pathological diameter were subjected to comparative analysis. Results Patients diagnosed with cholesterol polyps were younger in age and had higher BMI, and the total cholesterol levels and white blood cell levels were higher, but were not statistically significant. It was notable to see that 28.6% of the cholesterol polyps were not found in the preoperative CT yet the percentage of the undetectable rate was significantly lower (8%) in the non-cholesterol polyp group. There was a discrepancy in maximum diameters between the two radiological methods in both groups but the discrepancy was significantly larger in the cholesterol polyp group. Conclusion The clinical signs that can be helpful to diagnose whether it is a cholesterol polyp or not are younger patients who have high BMI, polyps which are detectable only on the USG and large maximum diameters between the USG and CT. And if the discrepancy of the maximum diameter is lesser than 1mm the polyp may be considered as a non-cholesterol polyp.

show abstract

Strategy for discriminating cholesterol and premalignancy in polypoid lesions of the gallbladder: a single‐centre, retrospective cohort study

Sun

Jiang

et al. 2018

ANZ Journal of Surgery

View full text Add to dashboard Cite

Background: The present study aimed to assess the risk factors of cholesterol and premalignancy in polypoid lesions of the gallbladder (PLGs) and to establish an appropriate treatment strategy. Methods: Data from patients who underwent cholecystectomy at the First Affiliated Hospital, School of Medicine, Zhejiang University, between January 2011 and July 2017, were collected retrospectively. Results: A total of 1561 patients were included in the present study. The cohort comprised of 636 (40.7%) males and 925 (59.3%) females, with a mean age of 49.5 (range 16-88) years; 65.6% (1024/1561) demonstrated cholesterol lesions in this cohort, among which cholesterol polyps accounted for 81.0%. Age younger than 50 years and multiple number of polyps were found to be independent predictive variables for cholesterol lesions (odds ratio (OR) 3.461, 95% confidence interval (CI) 2.058-5.820, P < 0.001 and OR 3.321, 95% CI 1.988-5.547, P < 0.001, respectively). The presence of polyp growth was associated with premalignancy (OR 5.366, 95% CI 1.466-19.637, P = 0.011), and the presence of clinical symptoms indicated benign non-cholesterol lesions (OR 0.368, 95% CI 0.153-0.885, P = 0.026). Conclusion: In the case of patients ≥50 years old with single asymptomatic polyp, cholecystectomy was recommended if the polyp presented growth at a rate above 3-4 mm within 6 months. If not, trimonthly ultrasound follow up was recommended, and clinicians should carefully assess the risk factors for premalignancy in PLGs.

show abstract

"Pólipos da vesícula biliar: e quando tratar?"

Cited by 3 publications

References 6 publications

Diagnosis and Management of Gallbladder Polyps

Diagnosis and Management of Gallbladder Polyps

Clinical and radiologic preoperative predicting factors for GB cholesterol polyp

Strategy for discriminating cholesterol and premalignancy in polypoid lesions of the gallbladder: a single‐centre, retrospective cohort study

Contact Info

Product

Resources

About