Saliva and oral health

Acevedo, Ana Carolina

doi:10.1590/s0104-42302010000100001

Cited by 14 publications

(8 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…It is an inexpensive, stress-free, and non-invasive method. 8,24,25 A pilot study was able to associate pain with SOD, 8-OHdG, and TAC, both in blood and in saliva. 25 Another study found the same amount of a biomarker of oxidative process, both in synovial fluid and in blood.…”

Section: Discussionmentioning

confidence: 99%

Changes in the salivary oxidative status in individuals with temporomandibular disorders and pain

Almeida

Amenábar

2016

Journal of Oral Biology and Craniofacial Research

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Changes in the salivary oxidative status in individuals with temporomandibular disorders and pain

Almeida

Amenábar

2016

Journal of Oral Biology and Craniofacial Research

View full text Add to dashboard Cite

“…As documented in previous reports 39 , 40 , saliva plays a key role in maintaining oral health and serves as an aid to oral diagnosis via flow rate and composition which are recognized as important markers against dental caries 41 . In this study, the salivary flow rate decreased significantly from healthy controls to the diseased groups.…”

Section: Discussionmentioning

confidence: 82%

Oral dysbacteriosis in type 2 diabetes and its role in the progression to cardiovascular disease.

2018

View full text Add to dashboard Cite

BackgroundSalivary changes and proliferation of specific bacterial communities are known to result in oral disease which may adversely impact on systemic conditions like diabetes and cardiovascular diseases.ObjectivesThis study reports on the changes in oral ecology of healthy and diseased adults and the possible role in disease causation.MethodsThe study comprised 150 participants divided into control (healthy), diabetic and cardiac groups. After dental examination for (Decayed Missing Filled Teeth (DMFT) and Oral Rating Index (ORI), stimulated saliva was sampled to determine flow rate and buffering capacity. Salivary microbial load of Streptococcus mutans and Lactobacilli were subsequently quantified.ResultsDMFT, ORI, buffering capacity and flow rate were inferior for both diabetic and cardiac patients, who had higher bacterial counts (p<0.05). Long standing diabetics harboured a higher load of Streptococcus mutans. The microbial load of Streptococcus mutans in cardiac patients was double that of diabetics.ConclusionDisruption in the salivary environment and changes in microbial ecology with increased load of cariogenic bacteria were found in diabetic and cardiac patients. This study brings forward new evidence of a markedly higher load of Streptococcus mutans in cardiac patients which may underlie the progression of diabetes to cardiovascular disease in this population.

show abstract

“…Sufficient salivary flow and composition are important for the lubrication and protection of oral tissue against desiccation, penetration, ulceration, and potential carcinogens by mucin and anti-proteases [14]. Saliva includes various components, including histatins, anti-bacterial polypeptides, acidic proline-rich proteins (PRPs), mucins, glycoproteins responsible for the viscosity of mucosal secretions, lysozyme, secretory immunoglobulin A (slgA), cystatins, α-amylase, kallikreins, etc.…”

Section: Biochemistry Of Salivamentioning

confidence: 99%

The significance of teaching human biochemistry to dental students

Ahsan¹

2021

Int J Med Biochem

View full text Add to dashboard Cite

The significance of teaching human biochemistry to dental students U ndergraduate students of medical sciences are required to apply professional and scientific knowledge in competence-based clinical skills acquired through laboratory training and patient interaction. Scientific and technological developments in medical sciences should be included in academic and clinical programs. Advancements in molecular biology, biochemistry, genomics, proteomics, and tissue engineering provide the basis for the use of new technologies in medicine. Laboratory sciences and research education is an important aspect of a health science curriculum and includes biomedical sciences and clinical biochemistry [1]. Knowledge of advanced medical biochemistry and laboratory clinical biochemistry is now an important aspect of medical and surgical disciplines (Fig. 1). The clinical biochemistry contribution of the analysis of glycated hemoglobin (HbA1c) to the diagnosis and monitoring of diabetes mellitus (DM) is particularly valuable. The importance of a serum lipid profile, including cholesterol and lipoproteins, for public health has increased enormously, as it identifies a risk factor for cardiovascular disease. Point-ofcare testing, i.e., the development of a wide range of portable instruments, analyzers, and test kits, which allows for emergency testing of patients in hospitals or self-testing by individuals, was a substantial methodological development [2]. Biochemistry in dentistryMedical sciences and therapeutics have progressed enormously over the last half a century, including the subject Objectives: Biochemistry instructions in dental studies should highlight the fact that the basic biochemical processes occurring in the oral cavity are the same as those that take place in other tissues and organs of the body. Saliva is a complex fluid that plays an essential role in the maintenance of oral health and contains a wide range of proteins, enzymes (lysozyme, lactoferrin, peroxidases) and secretory immunoglobulins. Salivary cationic peptides and defense proteins, such as lysozyme, salivary amylase, cystatins, mucins, peroxidases, and statherin, are primarily responsible for innate immunity. The role of collagen, which forms a large part of the organic material of dentin, should be given prominence in the study of proteins. The study of carbohydrates and lipids is also an important topic, since the digestion of starch and lipids begins in the oral cavity due to the presence of various enzymes, e.g., amylase and lipase. The biochemistry syllabus for dental sciences should also include the role of weak acids and bases and buffers to help students understand the buffering capacity of saliva and its implications for oral health. Patients with poor glycemic control are more prone to oral manifestations of diabetes, including periodontal disease, salivary gland dysfunction, halitosis, burning mouth sensation, delayed wound healing, and increased susceptibility to infection. Diabetic patients are also at greater risk of an intraoperative d...

show abstract

Saliva and oral health

Cited by 14 publications

References 7 publications

Changes in the salivary oxidative status in individuals with temporomandibular disorders and pain

Changes in the salivary oxidative status in individuals with temporomandibular disorders and pain

Oral dysbacteriosis in type 2 diabetes and its role in the progression to cardiovascular disease.

The significance of teaching human biochemistry to dental students

Contact Info

Product

Resources

About