Detecção sorológica de anti-HPV 16 e 18 e sua associação com os achados do papanicolaou em adolescentes e mulheres jovens

Rama, Cristina Helena; Roteli-Martins, Cecília Maria; Derchain, Sophie; Oliveira, Eliane Regina Zambelli Mesquita de; Aldrighi, José Mendes; Neto, Corintio Mariani

doi:10.1590/s0104-42302006000100021

Cited by 23 publications

(13 citation statements)

References 15 publications

(27 reference statements)

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“…10,12,19 This fi nding confi rms what is already known on the natural history of this condition which is characterized by higher infection rates after sexual initiation.…”

Section: Discussionsupporting

confidence: 77%

Prevalência do HPV em mulheres rastreadas para o câncer cervical

et al. 2008

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OBJECTIVE:To assess the prevalence of high-risk genital human papillomavirus (HPV) infection by age group and risk factors associated. METHODS:Cross-sectional study in a sample of 2,300 women (15-65 years old) who self-referred to cervical cancer screening in Sao Paulo and Campinas, Southeastern Brazil, between February 2002 and March 2003. An epidemiological questionnaire was applied and cervical specimens were obtained for cytology and hybrid capture II test (HCII) for HPV detection. Statistical analysis included Pearson Chi-square and unconditional multiple logistic regression model (forward likelihood ratio). RESULTS:High-risk genital HPV infection prevalence in this sample was 17.8% and age distribution was as follows: 27.1% (<25 years), 21.3% (25-34 years), 12.1% (35-44 years), 12.0% (45-54 years) and 13.9% (55-65 years). Subjects with the highest number of lifetime sexual partners had the highest rates of genital HPV infection. To be living with a partner, aged 35 to 44 years, and former smokers were protective factors. High-risk genital HPV infection was 14.3% in normal cytology, 77.8% in high grade squamous intraepithelial lesions and in the two cases (100%) of cervical cancer. CONCLUSIONS:High-risk HPV prevalence was high in the sample studied. The highest prevalence of HPV infection was seen in women under 25 years old and then a new increase was seen over the age of 55 and the highest rates were found among those with many sexual partners during their lifetime.

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“…10,12,19 This fi nding confi rms what is already known on the natural history of this condition which is characterized by higher infection rates after sexual initiation.…”

Section: Discussionsupporting

confidence: 77%

Prevalência do HPV em mulheres rastreadas para o câncer cervical

et al. 2008

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“…The principal risk factors associated with cervical cancer include human papillomavirus virus (HPV), early sexual initiation (< 16 years), numerous sex partners (more than four), genital warts, and smoking 4 . This calls attention to the potential use of measures to avert these risk factors and thus decrease the incidence of cervical cancer.…”

Section: Introductionmentioning

confidence: 99%

Cervical cancer mortality trends in Brazil: 1980-2009

et al. 2013

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The objective was to describe time trends in cervical cancer mortality rates in Brazil as a whole and in the country's major geographic regions and States from 1980 to 2009. This was an ecological time series study using data recorded in the Mortality Information System (SIM) and census data collected by the Brazilian Institute of Geography and Statistics (IBGE). Analysis of mortality trends was performed using Poisson regression. Cervical cancer mortality rates in Brazil tended to stabilize. In the geographic regions, a downward trend was observed in the South (-4.1%), Southeast (-3.3%), and Central-West (-1%) and an upward trend in the Northeast (3.5%) and North (2.7%). The largest decreases were observed in the States of São Paulo (5.1%), Rio Grande do Sul, Espírito Santo, and Paraná (-4.0%). The largest increases in mortality trends occurred in Paraíba (12.4%), Maranhão (9.8%), and Tocantins (8.9%). Cervical cancer mortality rates stabilized in the country as a whole, but there was a downward trend in three geographic regions and 10 States, while two geographic regions and another 10 States showed increasing rates.

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“…A infecção prévia pelo papiloma vírus humano (HPV) tem sido apontada como o principal fator de risco para o câncer de colo de útero 1,3,4,5,6 . No entanto, fatores como início precoce da atividade sexual, multiplicidade de parceiros sexuais, uso de contraceptivos orais, tabagismo, situação conjugal e baixa condição sócio-econômica têm sido apontados como fatores de risco importantes para o desenvolvimento dessa neoplasia 7,8 .…”

Section: Introductionunclassified

Cobertura do teste de Papanicolaou e fatores associados à não-realização: um olhar sobre o Programa de Prevenção do Câncer do Colo do Útero em Pernambuco, Brasil

et al. 2009

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Buscou-se avaliar a cobertura do teste Papanicolaou no Estado de Pernambuco, Brasil, nos três anos anteriores à pesquisa, entre mulheres de 18-69 anos, e identificar fatores associados à sua não-realização. Trata-se de um estudo transversal, de base populacional, utilizando-se dados de inquérito realizado no período 2005-2006 com 640 indivíduos, selecionados por amostragem por conglomerados em três estágios de seleção. Foram analisadas informações sobre 258 mulheres. A cobertura do Papanicolaou entre mulheres de 18-69 anos foi de 58,7% e de 25-59 anos de 66,2%. Viver sem companheiro, não ter dado à luz e não ter realizado consulta médica no último ano mostraram associação com a não-realização do teste. Na análise multivariada, o baixo grau de escolaridade mostrou também efeito significativo. A cobertura do Papani-colaou em Pernambuco foi satisfatória, porém insuficiente para impactar no perfil epidemiológico do câncer do colo uterino. É preciso fortalecer e qualificar as ações de promoção da saúde, visando reduzir as desigualdades e estimular o protagonismo das mulheres nas ações de prevenção do câncer do colo uterino.

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Detecção sorológica de anti-HPV 16 e 18 e sua associação com os achados do papanicolaou em adolescentes e mulheres jovens

Abstract: Results of this study indicate a high prevalence of HPV 16 and 18 in young healthy women which showed no relation to the abnormal findings of cytology smears.

Cited by 23 publications

References 15 publications

Prevalência do HPV em mulheres rastreadas para o câncer cervical

Prevalência do HPV em mulheres rastreadas para o câncer cervical

Cervical cancer mortality trends in Brazil: 1980-2009

Cobertura do teste de Papanicolaou e fatores associados à não-realização: um olhar sobre o Programa de Prevenção do Câncer do Colo do Útero em Pernambuco, Brasil

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