Melanoma metastático para vesícula biliar simulando litase vesical

Lajolo, Paula Philbert; Giglio, Auro del; Speranzini, Manlio Basílio; Rosseti, Claudia; Pettinati, Juliana

doi:10.1590/s0104-42302005000200012

Cited by 3 publications

(1 citation statement)

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“…If so, it usually presents with abdominal pain [6, 8, 11, 12, 17, 18, 20-23, 26-28, 33, 37-42, 46, 48, 49, 51, 53, 59-91]. Other observed symptoms are nausea and vomiting [8,73,75,78,79,84,86,91,92], jaundice [81,83], fever [79,83,89], tarry stools [11,19,36,93], hematemesis [19], hematobilia [93], and weight loss [5,6,16,22,51,84,84]. Physical examination usually is unremarkable.…”

Section: Signs Symptoms and Laboratory Findingsmentioning

confidence: 99%

Melanoma of the gallbladder

2023

Folia Medica Cracoviensia

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Melanoma is a highly malignant neoplasm with the most typical primary locations in the skin and eyeball and rarely reported in the other organs, including the gallbladder. More commonly metastases of melanoma of various primary sites to the gallbladder are observed. However, generally melanoma of the gallbladder is a rare entity with only 217 cases reported in the literature up to date. The paper summarizes knowledge on epidemiology, symptoms, laboratory and imaging findings, morphology, treatment options, and outcome of patients with both primary and metastatic melanoma to the gallbladder.

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Section: Signs Symptoms and Laboratory Findingsmentioning

confidence: 99%

Melanoma of the gallbladder

2023

Folia Medica Cracoviensia

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Melanocytic, Neuroectodermal, Germ Cell, Rhabdoid, Perivascular Epithelioid Cell, Hemolymphatic, and Metastatic Tumors of the Gallbladder

Zimmermann¹

2016

Tumors and Tumor-Like Lesions of the Hepatobiliary Tract

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The gallbladder is involved by a wide variety of non-epithelial tumors, apart from mesenchymal neoplasms. Visceral malignant melanoma develops in the biliary tract, including the gallbladder. As both primary and metastatic gallbladder melanomas may show similar of the same growth patterns, the differential diagnosis between these two conditions is often difficult. Primary gallbladder melanoma is more likely if the tumor shows a polypoid or lobulated and in particular papillary growth pattern, is a solitary lesion, and is associated with junctional activity in the adjacent mucosa. In contrast, metastatic lesions are more commonly multiple, flat, and without junctional changes. Apart from neuroendocrine tumors, other neuroectodermal neoplasms can develop as primary tumors in the gallbladder. Rare primary neoplasms in this organ include germ cell tumors, rhabdoid tumors, perivascular epithelioid cell tumors, and hemolymphatic neoplasms. Apart from malignant melanoma, numerous other malignancies can metastasize to the gallbladder, renal cell carcinoma being a particularly common metastasizing tumor. Malignant Melanoma of the Gallbladder Pathogenic Pathways Few melanocytes are present in the normal gallbladder mucosa, and it has been suggested that malignant melanomas take their origin from these cells that have spread from the neural crest to the gallbladder during oncogenesis. Primitive Neuroectodermal Tumor (PNET) of the Gallbladder Differential Diagnosis Differential diagnosis on conventionally stained sections mainly includes other small cell tumors occurring in the gallbladder, e.g., small cell carcinoma or lymphoma. Differential Diagnosis Gallbladder paraganglioma may occur as a component of multiple paragangliomas, involving the common bile duct and the liver in addition to the gallbladder (Ferrell et al. 1990).

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Melanocytic, Neuroectodermal, Germ Cell, Rhabdoid, Perivascular Epithelioid Cell, Hemolymphatic, and Metastatic Tumors of the Gallbladder

Zimmermann

2016

Tumors and Tumor-Like Lesions of the Hepatobiliary Tract

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Melanoma metastático para vesícula biliar simulando litase vesical

Cited by 3 publications

References 0 publications

Melanoma of the gallbladder

Melanoma of the gallbladder

Melanocytic, Neuroectodermal, Germ Cell, Rhabdoid, Perivascular Epithelioid Cell, Hemolymphatic, and Metastatic Tumors of the Gallbladder

Melanocytic, Neuroectodermal, Germ Cell, Rhabdoid, Perivascular Epithelioid Cell, Hemolymphatic, and Metastatic Tumors of the Gallbladder

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