Achados oftalmológicos em infectados pelo HIV na era pós-HAART e comparação com série de pacientes avaliados no período pré-HAART

Abstract

The authors identified in the post-HAART era, rise on number of patients with normal ophthalmologic exam and decreased number of cases of CMV retinitis and ocular toxoplasmosis when compared to the pre-HAART era.

Ocular problems in brazilian patients with AIDS before and in highly active antiretroviral therapy (HAART) era

“…Considering the total frequency of ocular problems and of cytomegalovirus retinitis in particular, our results were similar to the ones reported by Arruda, Muccioli and Belfort Jr., in São Paulo city [13]. However, the type and frequency of other ocular diseases were different.…”

“…With introduction of highly active antiretroviral therapy (HAART), changes in the frequency and type of ocular manifestations have occurred, with emphasis on the reduction of opportunistic infections [10][11][12][13][14][15][16][17][18][19] and on the onset of immune recovery uveitis [20][21][22][23].…”

“…In Brazil, investigators of the Federal University of São Paulo compared the profile of ophthalmologic problems of 200 patients attended at the uveitis/AIDS sector over a period of 1 year with the profile of patients studied in two previous investigations [6,8] and observed that during the post-HAART period there was a tendency to a reduction of the number of patients with cytomegalovirus retinitis and to an increase of patients with normal ophthalmologic examinations [13].…”

Avaliação oftalmológica em pacientes com AIDS e neurotoxoplasmose

“…Classificando em categorias as lesões oculares, que acometem pacientes com AIDS 14 , constituíram-se manifestações decorrentes de alteração da microvasculatura os exsudatos algodonosos retinianos, o macroaneurisma e a constrição arteriolar; as alterações oculares por infecções oportunistas secundárias à AIDS incluíram a retinocoroidite cicatricial, característica da toxoplasmose e o descolamento de retina, atribuído à uveíte posterior, decorrente de infecção por Citomegalovírus. Como alteração neuroftalmológica foi diagnosticado o papiledema.…”

Influência da forma infectante do Toxoplasma gondii na doença aguda humana: revisão sistemática de surtos epidêmicos

“…Toxoplasmose ocular tem sido relatada em 4-8% de pacientes com AIDS (Rehder et al, 1988;. Muccioli et al, 1994;Matos et al, 1999;Arruda et al, 2004;Zajdenweber et al, 2005;Alves et al, 2010a,b), incluindo uma criança com 13 meses de idade da (Moraes, 1999).…”