“…Although pulse oximetry is simple, it may give incorrect and unreliable results (diagnostic errors) in some conditions such as oxygen saturation below 70%, nail polish, environment light (e.g., operation lamp, florescent lamp, fiber devices), movement of sensor, incompatibility of sensor with device, shock with decline in tissue perfusion, skin pigmentation, carboxy hemoglobin, methemoglobin, anemia, raised blood lipids, raised blood bilirubin, no calibration of device, and intravenously injected dye. [45] Since pulse oximeter probes are most commonly applied over the fingernails, it has been a concern that nail polish may hinder light transmission. [6] Some studies indicated clinically significant decline in oxygen saturation (5%–10%) due to nail polish,[789] whereas some of them have demonstrated the accuracy of pulse oximetry measurement even with black, blue, and purple nail polish.…”