The utilization of mixed methods in prehospital research is relatively new. Its use may enhance research findings, but it is not without its challenges. This study used online databases to systemically search for literature relating to the application of mixed methods in prehospital research, in order to understand the place of mixed methods research in the prehospital setting. The prehospital field appears to be embracing mixed methods as an approach to research due to its ability to address health care questions in complex, diverse environments. However, supplemental literature in this area is limited, with mixed methods expertise being found in other health science areas. Researchers should endeavor to continue to contribute to this area through high-quality, rigorous mixed methods studies.Keywords prehospital, paramedic, mixed methods research, mixed methods, prehospital research Prehospital care takes place in the dynamic, out-of-hospital environment. It is provided within communities by trained health care professionals for ''analytic, resuscitative, stabilizing or preventative purposes'' before and during transportation to a medical facility (Loyola Emergency Medical Services System Policy and Procedure Manual, 2009). Prehospital care has an incredibly wide scope-paramedics manage injuries and illnesses ranging from the very minor to the immediately life-threatening, in a range of environments and conditions, with time and resource constraints. Likewise, parameters for prehospital research are extraordinarily wide, with researchers investigating topics from clinical, systems-related, and educational standpoints.The utilization of mixed methods in prehospital research is relatively new for two reasons. First, prehospital research is embryonic and evolving. Second, much of the prehospital research