Advances in the biomedical applications of reactive colloids

Abstract

This short review aimed to give to reader's brief applications of polymer colloids in biomedical area such as therapy and medical diagnosis as also developed in our laboratory. Indeed, the polymer particles and composite particles are commonly used in immunoassays as solid phase supports, for the encapsulation of active agents and for the immobilization of biomolecules such as oligonucleotides, proteins or antibodies. In the area of composite particles, magnetic particles bearing immobilized biomolecules are used in biomedical diagnosis such as immunoassay, specific nucleic acids concentration, cell labelling and separation and in numerous biotechnological applications.

Preparation and characterization of submicron hybrid magnetic latex particles

“…However, such applications require different tedious and time consuming separation processes, mainly when two kinds of separation processes are used, i.e. (a) filtration and (b) centrifugation . These processes limit the automation of biomedical diagnosis resulting in loss of time and delay in diagnosis .…”

“…(a) filtration and (b) centrifugation. [4] These processes limit the automation of biomedical diagnosis resulting in loss of time and delay in diagnosis. [5] Although magnetic latex particles are overcoming these methods, improving the process of automation while also decreases time delay and providing fast particles separation upon applying even low magnetic field.…”

On the Size‐Determining Role of the Comonomer in the Nucleation and Growth of Cationic Polystyrene Latex via Emulsion Polymerization

“…These techniques have enabled the precise synthesis of colloidal particles with adjustable dimensions in the nanometer scale and very low polydispersity. Reasons for the ongoing interest in polystyrene (PS) particles include their high potential for use in different scientific areas, for example, in imaging techniques for biomedical applications, the immobilization, and separation of biomolecules, or the design of catalytically active nanoparticles . Moreover, they can serve as precision core particles for further functionalization, especially for the synthesis of patchy particles, core/shell particles, or colloidal molecules .…”