We demonstrate that under the "symmetric zero texture" with minimal Majorana mass matrix, neutrino masses and mixing angles are expressed in terms of up-quark masses, m t , m c , m u . This provides interesting relations among neutrino mixing angles and up-type quark masses. Especially we predict |U e3 | ≤ 0.11 even if we include the small mixing effects coming from charged lepton side. Also absolute masses of three neutrinos are predicted almost uniquely. This is quite in contrast to the case where bi-large mixings come from the charged lepton sector with non-symmetric charged lepton mass matrix.