Systems Biology: an information-theoretic-based thermo-statistical approach

Mesquita, Marcus V.; Vasconcellos, Áurea R.; Luzzi, Roberto; Mascarenhas, S.

doi:10.1590/s0103-97332004000300027

Cited by 21 publications

(18 citation statements)

References 69 publications

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“…Reimers (2009) have properties of specific energy sources as reported by Mesquita et al (2004) by which, weak coherent condensates within individual proteins may be feasible. They also showed how weak condensation can lead to a significant deviation from the simple steady-state, expected when biochemical processes provide energy to an enzyme.…”

Section: The Role Of Informational Ca2+ Ion Messenger In the Creationmentioning

confidence: 99%

Phonon Guided Biology. Architecture of Life and Conscious Perception Are Mediated by Toroidal Coupling of Phonon, Photon and Electron Information Fluxes at Discrete Eigenfrequencies.

Meijer

Geesink

2016

Neuroquantology

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Recently, a novel biological principle, revealing specific electromagnetic (EM) radiation frequencies that sustain life, was presented by us on the basis of an evaluation of 175 biological articles concerning beneficial effects of electromagnetic waves on the state of living cells. This concept was also based on a very similar range of frequencies emitted by a clay-mineral catalyst of RNA synthesis that may have been instrumental in the evolutionary initiation of first life, and therefore was tentatively designated as "Algorithm of Life". The particular spectrum of frequency bands indicate that nature seems to employ discrete eigenfrequencies or standing waves that match precisely with an acoustic scale, with frequency ratios of 1:2, and closely approximated by 2:3, 3:4, 3:5, 4:5 and higher partials, allowing the discrete frequencies to be expressed in scalars. Our further studies clearly indicate now that this "life algorithm" pattern matches very well with the mathematical calculations of W. Ritz (1909) to compute eigenfrequencies of the sound induced geometric patterns. These have been earlier demonstrated through membrane vibration experiments of E. Chladni (1787), as well as several follow up studies from 1970-2013. Our findings, therefore, touch upon the science of acoustics, also since we show that the discrete frequencies could be modeled by music torus geometry. We postulate that the spectrum of EM frequencies detected, exhibit a quantum ordering effect on life cells on the basis of induction of geometric wave patterns. These constitute phonon/photon and electron wave energies, and quantum oscillations at far-infrared frequencies, that are communicated through toroidal constructive interference into scalar wave information. This idea is supported through our identification of potential intrinsic toroidal eigenfrequencies and minimal energy levels. The particular torus topology for information processing may also provide quantum error correction and protection against decoherence. Finally, we propose a phonon guided organization of cells and integral brain function by three elementary processes: 1) A phonon mediated geometric organization of coherent arrangement of water molecules in cellular plasma, leading to instructive functional organization of cellular structures and metabolic processes and enabling the origination and sustainment of life processes. 2) Toroidal phonon/photon/electron coupling, protecting standing wave coherency of resonant cell components such as proteins and DNA. 3) A toroidal integration of electromagnetic and phononic fluxes of information into scalar standing waves, promoting quantum flux of informational excitons such as Ca2+-ions and electrons (polaron and polariton formation). Our brain, therefore, can be placed in a 4+1 geometry, supported by internal and external quantum states and makes use of geometrical defined information fluxes, that are converted to standing waves. The integration of these interrelated processes is considered to be instrumental in the creatio...

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Section: The Role Of Informational Ca2+ Ion Messenger In the Creationmentioning

confidence: 99%

Phonon Guided Biology. Architecture of Life and Conscious Perception Are Mediated by Toroidal Coupling of Phonon, Photon and Electron Information Fluxes at Discrete Eigenfrequencies.

Meijer

Geesink

2016

Neuroquantology

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“…The reason that water plays an important role in life is because in living systems it is known to support coherent dipolar excitations where the Fröhlich effect has a connection with long range propagation of signals in biological and nonbiological materials as wave packets consisting Schrodinger Davydov solitons (Mesquita et al, 2004;2005;Fröhlich Centenary International Symposium, 2005). Excitations are of great importance in the migration of energy and for the quantum computation of early life.…”

Section: Quantum Biologics Led To the Origin Of Life And Consciousnesmentioning

confidence: 99%

Origin of Life: A Consequence of Cosmic Energy, Redox Homeostasis and Quantum Phenomenon

Reddy

Pereira

2016

Neuroquantology

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Origin of life on earth transpired once and from then on, it emerges as an endless eternal process. Matter and energy are constants of the cosmos and the hypothesis is that the origin of life is a moment when these constants intertwined or interacted. Energy from the cosmos interacted with inorganic matter to support matter with retention of this riveted energy, as energy to be circulated within the primitive channelized structures to conserve energy by the materialization of the proton homeostasis mechanisms developed from the obtainable inorganic matter. The driver for these processes as we now confirm, exists in the quantum world and through quantum phenomenal processes could have combined these constants to create the magic of life. Primitive earth was a chemical reactive system that triggered a macromolecular evolution by means of open thermodynamic systems, driven by cyclic gradients of temperature, electromagnetic radiation and chemical potentials which sustained life and proto-consciousness in the first life forms driven by the quantum processes. The origin of life is always an intriguing topic but the purpose for finding the cause should never be inclined towards obliterating it; for if that is the case, the further we seek, the farther it will go.

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“…In Refs. [158][159][160][161][162][163][164][168][169][170][171][172][173] is given an overview of the role of the irreversible thermodynamics based on NESEF in dealing with biosystems. On the question of the relation of Biology and Physics we may say that the sometimes mentioned gap between both disciplines has been slowly shrinking along recent decades.…”

Section: Coherent States and Nonequilibrium Bose-einstein-like Conmentioning

confidence: 99%

“…The question was further pursued in [158,[168][169][170][171][172], where the above mentioned Fröhlich effect -consisting, as noticed, of a coherent behavior of boson-like excitations in biological and molecular polymers -is fully derived and analyzed in terms of NESEF. It was shown that when double (or multiple) processes of excitation of the boson system are possible there follows a positive-feedback phenomenon that greatly favors and enhances the effect [174].…”

Section: Coherent States and Nonequilibrium Bose-einstein-like Conmentioning

confidence: 99%

“…Refs. [158][159][160][168][169][170][171][172][181][182][183][184]) phonon systems [162][163][164], and magnon systems [161]. It can also be noticed that the NESEF-based nonlinear quantum kinetic theory provides, as particular limiting cases, farreaching generalizations of Boltzmann and Mori equations [67][68][69]71] and a Higher-Order Hydrodynamics, linear and nonlinear [85,133,134].…”

Section: Thermo-statistics Of Complex Structured Systems and Nesefmentioning

confidence: 99%

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The role of nonequilibrium thermo-mechanical statistics in modern technologies and industrial processes: an overview

Rodrigues¹,

Silva²,

Silva³

et al. 2010

Braz. J. Phys.

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The nowadays notable development of all the modern technology, fundamental for the progress and well being of world society, imposes a great deal of stress in the realm of basic Physics, more precisely on ThermoStatistics. We do face situations in electronics and optoelectronics involving physical-chemical systems farremoved-from equilibrium, where ultrafast (in pico-and femto-second scale) and non-linear processes are present. Further, we need to be aware of the rapid unfolding of nano-technologies and use of low-dimensional systems (e.g., nanometric quantum wells and quantum dots in semiconductor heterostructures). All together this demands having an access to a Statistical Mechanics being efficient to deal with such requirements. It is worth noticing that the renowned Ryogo Kubo once stated that "statistical mechanics has been considered a theoretical endeavor. However, statistical mechanics exists for the sake of the real world, not for fictions. Further progress can only be hoped by close cooperation with experiment". Moreover, one needs to face the study of soft matter and fluids with complex structures (usually of the average self-affine fractal-like type). This is relevant for technological improvement in industries like, for example, that of polymers, petroleum, cosmetics, food, electronics and photonics (conducting polymers and glasses), in medical engineering, etc. It is then required to introduce a thermo-hydrodynamics going well beyond the classical (Onsagerian) one. Moreover, in the both type of situations above mentioned there often appear difficulties of description and objectivity (existence of so-called "hidden constraints"), which impair the proper application of the conventional ensemble approach used in the general, logically and physically sound, and well established Boltzmann-Gibbs statistics. A tentative to partially overcome such difficulties consists in resorting to non-conventional approaches. Here we briefly describe the construction of a Non-Equilibrium Statistical Ensemble Formalism (NESEF) that can deal, within a certain degree of success, with the situations above described. Several particular instances involving experimental observations and measurements in the area of semiconductor physics and in physics of fluids, which were analyzed in the context of the theory, are summarized. They comprise the cases of ultrafast optical spectroscopy; optical and transport processes in low-dimensional complex semiconductors; nonlinear transport in doped highly-polar semiconductors (of use in "blue diodes") under moderate to high electric fields; nonlinear higher-order thermo-hydrodynamics in fluids under driven flow, in normal solutions and in complex situations as in solutions of polymers, micelles, DNA, and in microbatteries.

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Systems Biology: an information-theoretic-based thermo-statistical approach

Cited by 21 publications

References 69 publications

Phonon Guided Biology. Architecture of Life and Conscious Perception Are Mediated by Toroidal Coupling of Phonon, Photon and Electron Information Fluxes at Discrete Eigenfrequencies.

Phonon Guided Biology. Architecture of Life and Conscious Perception Are Mediated by Toroidal Coupling of Phonon, Photon and Electron Information Fluxes at Discrete Eigenfrequencies.

Origin of Life: A Consequence of Cosmic Energy, Redox Homeostasis and Quantum Phenomenon

The role of nonequilibrium thermo-mechanical statistics in modern technologies and industrial processes: an overview

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