Blood gas analysis, anion gap, and strong ion difference in horses treated with polyethylene glycol balanced solution (PEG 3350) or enteral and parenteral electrolyte solutions

Gomes, Cláudio Luís Nina; Filho, José Dantas Ribeiro; Faleiros, Rafael Resende; Dantas, Fernanda Timbó D'el Rey; Amorim, L. S.; Dantas, Waleska de Melo Ferreira

doi:10.1590/s0103-84782014000600022

Cited by 2 publications

(2 citation statements)

References 19 publications

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“…The anion gap showed little variation throughout the experimental period and values remained in the normal range (24,26) in all three treatment groups. SID remained unchanged in the LR IV treatment group during the fluid therapy period and at the lower limit in EsHYPO.…”

Section: Phase With Eshypo and Esiso Reached Values Above Baseline (T-36hmentioning

confidence: 88%

“…The energy source of EsHYPO and EsISO treatments may have been the cause of the slight decrease in blood pH, HCO − 3 and BE observed. As mentioned by Gomes et al (24), the addition of carbohydrates in enteral solutions can lead to intestinal microbial fermentation and the production of organic acids, that are absorbed and might generate this effect. Even so, it is necessary to highlight that the effect of enteral electrolyte solutions on the referred variables was mild, especially in the EsHYPO group.…”

Section: Phase With Eshypo and Esiso Reached Values Above Baseline (T-36hmentioning

confidence: 98%

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Comparative Trial of Continuous Flow Enteral and Intravenous Fluid Therapy in Horses

et al. 2021

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Continuous flow enteral fluid therapy with isotonic and hypotonic enteral electrolyte solutions are as safe and effective as intravenous fluid therapy. The aim of this study was to carry out a comparative assessment between continuous flow enteral and intravenous (IV) fluid therapy in adult experimentally dehydrated horses. Six experimentally dehydrated adult mares were used in a study carried out in a 6 × 3 crossover design, which each animal received three different treatments (isotonic enteral fluid therapy—EsISO, hypotonic enteral fluid therapy—EsHYPO and intravenous fluid therapy with Lactate Ringer Solution—LR IV, all in continuous flow). Solutions were administered at a rate of 15 mL−1.kg−1.h−1 for 8 h, after 36 h of water and food deprivation. Serum and urinary biochemical assessment; urinary volume, pH and specific gravity; and blood gas analysis were measured at −36, 0, 2, 4, 6, and 8 h. The dehydration period (DP) caused discrete hydroelectrolytic and acid base imbalances. The EsISO, EsHYPO and LR IV increased blood volume. Enteral solutions restored the imbalances yielded by the DP and all treatments increased urine volume. Also, the EsHYPO and LR IV showed no effects in acid base balance, while EsISO showed slightly acidifying effect. The present study certifies the efficacy and safety of isotonic and hypotonic continuous flow enteral fluid therapy in comparison to IV fluid therapy in dehydrated horses.

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Section: Phase With Eshypo and Esiso Reached Values Above Baseline (T-36hmentioning

confidence: 88%

Section: Phase With Eshypo and Esiso Reached Values Above Baseline (T-36hmentioning

confidence: 98%

Comparative Trial of Continuous Flow Enteral and Intravenous Fluid Therapy in Horses

et al. 2021

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Maintenance enteral electrolyte solutions for neonatal calves: sodium acetate and osmolarity effects

Lima

Filho

Ermita

et al. 2020

Arq. Bras. Med. Vet. Zootec.

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The use of hypotonic electrolytic solutions in enteral fluid therapy is still understudied in calves. The objective of the present study was to evaluate the effects of maintenance enteral electrolytic solutions with different concentrations of sodium acetate and different osmolarities in calves. For this, 18 Holstein calves, six male and 12 female, 20 days old and weighing around 52kg, were used. The animals were randomly divided into three groups and each group received one of the treatments. The three electrolytic solutions contained the same components in different concentrations, resulting in a hyposmotic, an isosmotic and a hyperosmotic solution. Each animal was maintained in enteral fluid therapy for 12 hours with infusion rate of 15mL kg-1 h-1. Abdominal circumference, body weight, feces consistency, glucose and plasma lactate, pH, pCO2, HCO- 3 and BE were measured at the following times: T0h, T6h, T12h and T24h. The hyposmotic solution did not generate the onset of diarrhea, while the isosmotic and the hyperosmotic did. Regardless of the dose used, acetate did not cause metabolic alkalosis in the evaluated animals. The results suggest that the use of hyposmotic solution in diarrheic calves, dehydrated and without metabolic acidosis, may be clinically important.

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Blood gas analysis, anion gap, and strong ion difference in horses treated with polyethylene glycol balanced solution (PEG 3350) or enteral and parenteral electrolyte solutions

Abstract: Large volumes of different electrolytes solutions are commonly used for ingesta hydration in horses with

Cited by 2 publications

References 19 publications

Comparative Trial of Continuous Flow Enteral and Intravenous Fluid Therapy in Horses

Comparative Trial of Continuous Flow Enteral and Intravenous Fluid Therapy in Horses

Maintenance enteral electrolyte solutions for neonatal calves: sodium acetate and osmolarity effects

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