Líquido sinovial da articulação femuropatelar após desmotomia patelar medial experimental em eqüinos

Martins, Edivaldo Aparecido Nunes; Silva, Luís Cláudio Lopes Correia da; Baccarin, Raquel Yvonne Arantes

doi:10.1590/s0103-84782007000300028

Cited by 4 publications

(1 citation statement)

References 8 publications

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“…Joint inflammation caused by surgical aggression breaks the hyaluronate molecules, resulting in this change. The postsurgical reduction in viscosity should also be accompanied by an increase in overall cell count, which was verified during this experiment [12,21,22]. Surgical aggression, even when minimally invasive, promotes different degrees of synovitis, which results in synovial effusion and the influx of proteins and fibri- Means followed by same small letters down the column and capital letters along the row are not statistically different by the Tukey test (p > 0.05).…”

Section: Discussionsupporting

confidence: 62%

Mesenchymal stem cell enhances chondral defects healing in horses

Yamada¹,

Carvalho²,

Moroz³

et al. 2013

SCD

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The purpose of this study was to evaluate the effect of intralesional Mesenchymal Stem Cells (MSC) on the treatment of experimentally induced articular chondral defects in horses, emphasizing the benefits of this application in veterinary medicine. Chondral defects were induced in the medial femoral trochlea of both hind limbs of four horses. Thirty days post induction; the horses were divided into two groups. The G1 was submitted to treatment with MSC and the G2 was the control group. Clinical evaluations, synovial fluid analysis and synovial Prostaglandin E 2 (PGE 2 ) assessment were performed prior to defects and fortnightly up to 120 and 150 days.

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Section: Discussionsupporting

confidence: 62%

Mesenchymal stem cell enhances chondral defects healing in horses

Yamada¹,

Carvalho²,

Moroz³

et al. 2013

SCD

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A new heterologous fibrin sealant as a scaffold to cartilage repair—Experimental study and preliminary results

Barros

Yamada

et al. 2015

Exp Biol Med (Maywood)

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Autologous fibrin gel is commonly used as a scaffold for filling defects in articular cartilage. This biomaterial can also be used as a sealant to control small hemorrhages and is especially helpful in situations where tissue reparation capacity is limited. In particular, fibrin can act as a scaffold for various cell types because it can accommodate cell migration, differentiation, and proliferation. Despite knowledge of the advantages of this biomaterial and mastery of the techniques required for its application, the durability of several types of sealant at the site of injury remains questionable. Due to the importance of such data for evaluating the quality and efficiency of fibrin gel formulations on its use as a scaffold, this study sought to analyze the heterologous fibrin sealant developed from the venom of Crotalus durissus terrificus using studies in ovine experimental models. The fibrin gel developed from the venom of this snake was shown to act as a safe, stable, and durable scaffold for up to seven days, without causing adverse side effects. Fibrin gel produced from the venom of the Crotalus durissus terrificus snake possesses many clinical and surgical uses. It presents the potential to be used as a biomaterial to help repair skin lesions or control bleeding, and it may also be used as a scaffold when applied together with various cell types. The intralesional use of the fibrin gel from the venom of this snake may improve surgical and clinical treatments in addition to being inexpensive and adequately consistent, durable, and stable. The new heterologous fibrin sealant is a scaffold candidate to cartilage repair in this study.

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Utilização de contrairritante no tratamento da fixação dorsal de patela intermitente em equinos: relato de casos

Watanabe

Pyles²,

Alonso

et al. 2013

Arq. Bras. Med. Vet. Zootec.

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2 Médico veterinário autônomo -Botucatu, SP RESUMOEm nove equinos atendidos por apresentarem fixação dorsal de patela intermitente, optou-se pela aplicação de 2mL de contrairritante na região subcutânea, ao longo dos ligamentos patelares medial e intermédio. No período de 12 a 48h após a aplicação, os animais apresentaram aumento de volume e de temperatura local, sensibilidade dolorosa à palpação e relutância à locomoção. Após esse período, os sinais clínicos de inflamação e fixação dorsal de patela foram gradativamente diminuindo até o sétimo dia, em sete dos nove animais avaliados. Após a remissão dos sinais de inflamação, dois animais não responderam ao tratamento, sendo necessária a repetição em um dos casos e realização de desmotomia patelar medial no outro. A aplicação de contrairritante foi eficaz na remissão do sinal clínico de fixação dorsal da patela intermitente. Comparativamente às técnicas cirúrgicas para a correção da enfermidade descritas na literatura, o tratamento promoveu melhora precoce dos sinais, curto período de convalescência e praticidade na realização.Palavras-chave: fixação de patela, ligamentos patelares, tratamento conservativo, contrairritante ABSTRACT Nine horses were admitted showing intermittent lameness due to upward fixation of the patella (UFP) and were injected with 2mL of counter-irritant subcutaneously

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Líquido sinovial da articulação femuropatelar após desmotomia patelar medial experimental em eqüinos

Cited by 4 publications

References 8 publications

Mesenchymal stem cell enhances chondral defects healing in horses

Mesenchymal stem cell enhances chondral defects healing in horses

A new heterologous fibrin sealant as a scaffold to cartilage repair—Experimental study and preliminary results

Utilização de contrairritante no tratamento da fixação dorsal de patela intermitente em equinos: relato de casos

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