Implante ósseo cortical alógeno conservado em mel na reconstrução de falha óssea diafisária em fêmur de cães: avaliação clínica e radiográfica

Abstract

IVHoney preserved cortical allografts in the repair of diaphyseal femoral defect in dogs: clinical and radiographic evaluation

Estudo comparativo da resistência mecânica da força de compressão entre biomateriais naturais, sintéticos e mistos

“…Uma das principais opções para o tratamento dessas afecções é a substituição de um segmento ou o preenchimento de falha óssea, utilizando biomateriais natural ou sintético (Ranzani et al 1996, Alievi et al 2007, Freitas et al 2013. A melhor opção para se tratar as falhas ósseas recai sobre o uso de biomaterial autógeno, ou seja, auto-enxerto, já que acelera a cicatrização óssea.…”

“…Uma opção para a reparação das falhas ósseas seria o uso de biomateriais naturais, sintéticos ou mistos que apresentassem propriedades osteogênicas, osteoindutora e osteocondutora, que proporcionassem sustentação mecâni-ca, de fácil aquisição, baixo custo, que não necessitassem de material especializado para preservação, e que preenchessem completamente a falha óssea, eliminando problemas inerentes ao biomaterial autógeno (Sinibaldi 1989, Bauer & Muschler 2000, Alievi et al 2007, Freitas et al 2012, Fernandes et al 2014.…”

Comparison of lyophilization, and freezing in honey as techniques to preserve cortical bone allografts used to repair experimental femoral defects in domestic adult cats

“…Although allogeneic grafts have greater immune response when compared to autografts (Goldberg and Stevenson, 1987), the approach has produced satisfactory results (Alievi et al, 2007). These grafts can be osteoconductive, osteoinductive and provide mechanical support (Fitch et al, 1997).…”

“…Several methods and means for maintaining these grafts can be used, among which is preservation by freezing (Nather, 2001), lyophilization (Galia et al, 2009), glycerin (Del Carlo et al, 1999) and honey (Alievi et al, 2007). Freezing and lyophilization are successful in the preservation and incorporation of allografts, but require costly, sophisticated equipment (Del Carlo et al, 1999), which are obstacles as regards to the use of these methods in many hospitals and clinics.…”

“…Freezing and lyophilization are successful in the preservation and incorporation of allografts, but require costly, sophisticated equipment (Del Carlo et al, 1999), which are obstacles as regards to the use of these methods in many hospitals and clinics. Another option would be to conserve bone in honey, as this material is readily available, inexpensive, it does not require specialized equipment to be obtained (Amendola et al, 2003), apart from the fact that it exhibits antimicrobial properties both in vitro and in vivo (Cooper et al, 1999;Alievi et al, 2007). Among these properties are osmolarity (Cooper et al, 1999), production of hydrogen peroxide (Mendes e Coelho, 1983), low pH (Bergman et al, 1983), besides the presence of enzymes (Molan, 1992) and flavonoids (Sabatier et al, 1992) with antibacterial action.…”