Supplementation of dairy cows with propylene glycol during the periparturient period: effects on body condition score, milk yield, first estrus post-partum, beta-hydroxybutyrate, non-esterified fatty acids and glucose concentrations

Fonseca, Luís Fernando Laranja da; Rodrigues, Paulo Henrique Mazza; Santos, Marcos Veiga dos; Lima, André Pinto; Lucci, Carlos de Sousa

doi:10.1590/s0103-84782004000300037

Cited by 9 publications

(9 citation statements)

References 22 publications

(53 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…There were no differences in the number of open days between cows treated with PG and cows in the control group. Similar results were published by Laranja et al, (2004). This may be due to the fact that the energy contribution of the PG was only given until week 3 after delivery and the peak production occurs several weeks later, so the effect of the PG is not so prolonged.…”

Section: Discussionsupporting

confidence: 82%

“…These results are confirmed by Laranja et al, (2004) who reported that cows treated with PG had 0.3 more body condition score than control cows. It has been shown that the use of PG drastically reduces the mobilization of body fat in cows in the first weeks postpartum (Nielsen and Ingvartsen, 2004) and this can contribute to reduced cows losing body condition, which could be an advantage.…”

Section: Discussionsupporting

confidence: 74%

“…In addition, there is a publication of a meta-analysis that included 13 scientific publications and about two thousand cows, where the conclusion was that PG treatment increased milk production 2.1 kg per day (mentioned in: Nielsen and Ingvartsen, 1996). Although there are reports indicating that there is no benefit of treatment with PG in milk production (Laranja et al, 2004). Perhaps the difference between some studies may be due to the dose, duration and frequency of PG administration.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Beneficios del Propilenglicol en el Periparto en Cetosis Subclínica y Parámetros Productivos en el Trópico Veracruzano

et al. 2019

View full text Add to dashboard Cite

The effects of propylene glycol (PG) delivered in the peripartum, on body condition (CC), concentrations of β-hydroxybutyrate (BHBA), prevalence of subclinical ketosis (CS), milk production (PL) and open days (DA) were determined in multiparous dairy cows from the tropic of Veracruz. Three weeks before, the cows were randomly selected to receive 250 ml of PG / day (n = 18) or H2O (Control, n = 18) orally and continued with the treatment until the third week postpartum. The CC was measured every week and milk daily. Starting the week of delivery, a milk sample was taken weekly for 4 weeks to determine BHBA and prevalence of CS (BHBA ≥ 200μmol / l). The statistical analysis was performed using STATISTICA 7. The PG cows maintained better (P˂0.05) CC at the fourth postpartum week (3.21 ± 0.18) than the control cows (2.7 ± 0.18). PG cows had lower (P˂0.05) CS prevalence and BHBA concentrations (0% and 51.6 ± 41.0 μmol/l) than control cows (64% and 214.5 ± 41.6 μmol/l, respectively). The PG cows produced 933.2 more liters of milk / lactation. The DAs were similar (P = 0.10) in both groups. Concluding that the treatment with peripartum PG increased the milk production, decreased the concentrations of β-hydroxybutyrate and the prevalence of CS, maintained better the CC, but did not reduce the DA.Propylene glycol, subclinical ketosis, milk production, tropics. RESUMEN Se determinaron los efectos de propilenglicol (PG) suministrado en el periparto, en la condición corporal (CC), concentraciones de β-hidroxibutirato (BHBA), prevalencia de cetosis subclínica (CS), producción de leche (PL) y días abiertos (DA), en vacas lecheras multíparas del trópico veracruzano. Tres semanas preparto las vacas fueron seleccionadas aleatoriamente para recibir 250 ml de PG/día (n=18) o H2O (Control, n=18) vía oral y continuaron con el tratamiento hasta la tercera semana posparto. La CC se midió cada semana y la leche diariamente. Iniciando la semana del parto se tomó una muestra de leche semanalmente durante 4 semanas para determinar BHBA y prevalencia de CS (BHBA ≥ 200µmol/l). El análisis estadístico se realizó utilizando STATISTICA 7. Las vacas PG mantuvieron mejor (P˂0.05) CC a la cuarta semana posparto (3.21±0.18) que las vacas control (2.7±0.18). Las vacas PG tuvieron menor (P˂0.05) prevalencia de CS y concentraciones de BHBA (0% y 51.6±41.0 µmol/l) que las vacas control (64% y 214.5±41.6 µmol/l, respectivamente). Las vacas PG produjeron 933.2 más litros de leche/lactancia. Los DA fueron similares (P=0.10) en ambos grupos. Concluyendo que el tratamiento con PG periparto incrementó la producción de leche, disminuyó las concentraciones de β-hidroxibutirato y la prevalencia de CS, mantuvo mejor la CC, pero no redujo los DA.Propilenglicol, cetosis subclínica, producción de leche, trópico.

show abstract

Section: Discussionsupporting

confidence: 82%

Section: Discussionsupporting

confidence: 74%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Beneficios del Propilenglicol en el Periparto en Cetosis Subclínica y Parámetros Productivos en el Trópico Veracruzano

et al. 2019

View full text Add to dashboard Cite

show abstract

“…The NEFA values in high yielding dairy cows with low lipomobilization may be up to 250 µmol/L when energy balance is stabilized during lactation [ 9 ]. There are few works on the threshold of serum NEFA levels which identifies high lipomobilization in dairy cows, but Oetzel [ 13 ] noted that NEFA concentration > 400 µmol/L indicate problems with energy balance and subsequent intensive lipomobilization.…”

Section: Discussionmentioning

confidence: 99%

Relationship among blood indicators of lipomobilization and hepatic function during early lactation in high-yielding dairy cows

et al. 2011

View full text Add to dashboard Cite

Blood indicators are used as a tool to diagnose metabolic disorders. The present work was conducted to study the relationships among blood indicators of lipomobilization and hepatic function in high-yielding dairy cows. Two groups of Holstein cows were studied: 27 early lactation cows and 14 mid lactation cows from four different herds with similar husbandry characteristics in Galicia, Spain. Blood samples were obtained to measure beta-hydroxybutyrate (BHB), non-esterified fatty acids (NEFA), triglycerides (TG), and the activity of aspartate transaminase (AST) and gamma-glutamyl transferase. Cows in early lactation had higher levels of BHB and NEFA than mid lactation cows. High lipomobilization (NEFA > 400 µmol/L) was detected in 67% and 7% of early lactation and mid lactation cows, respectively, while subclinical ketosis (BHB > 1.2 mmol/L) was detected in 41% and 28% of the early lactation and lactation cows, respectively. TG concentrations were low in all cows suffering subclinical ketosis and in 61% of the cows with high lipomobilization. During early lactation, 30% of cows suffered hepatic lipidosis as detected by levels of AST. Compromised hepatic function was observed in early lactation cows as shown by lower concentrations of glucose, total protein, and urea.

show abstract

“…During the period of positive energy balance, dairy cows of high genetic merit have a low lipid mobilization, and NEFA concentration values are around 0.25 mM (Fonseca et al, 2004). Concentrations higher than 0.40 mM indicate NEB, and a high lipid mobilization (Oetzel, 2004).…”

Section: Discussionmentioning

confidence: 99%

Reference values for biochemical analytes in Mexican dairy farms: interactions and adjustments between production groups

Garcia

Prado

Galicia

et al. 2017

Arq. Bras. Med. Vet. Zootec.

View full text Add to dashboard Cite

Blood samples of 189 healthy Holstein cows classified as high-producers, low-producers, or dry cows, were collected with the purpose of establishing reference values for several biochemical analytes in Mexican dairy farms. Mean values were calculated for: 1) Energy profile: glucose, cholesterol, triglycerides, β-hydroxybutyrate, and non-esterified fatty acids, 2) Protein profile: urea, albumin, globulin, and total protein, 3) Mineral profile: calcium, phosphorus, sodium, potassium, magnesium, chlorine, carbon dioxide, bicarbonate, and anion gap, and 4) Hepatic enzyme: γ-glutamyl transpeptidase. The resulting data set was analyzed using Gaussian distribution and descriptive statistics. Confidence intervals of 95% were established. The linear relationships between the biochemical analytes were quantified, and an analysis of variance was performed to compare the mean values between the three production groups. The overall concentrations of the described analytes are consistent with values reported by international literature. However, lower values were found for urea, calcium, and sodium; higher values were found for cholesterol, and γ-glutamyl transpeptidase. Negative correlations were found between β-hydroxybutyrate and glucose or urea, γ-glutamyl transpeptidase and urea, and bicarbonate and urea or phosphorus or anion gap. Positive correlations were found between β-hydroxybutyrate and cholesterol or anion gap, non-esterified fatty acids and anion gap, cholesterol and globulin, different analytes of mineral profile and anion gap or urea or glucose, and between sodium and calcium. Differences among the three production groups were observed for β-hydroxybutyrate and cholesterol concentrations. The γ-glutamyl transpeptidase concentration was similar in high and low-producing cows but was higher in comparison to serum levels of dry cows. Calcium showed differences between high-producing cows and the other two groups, and sodium showed the highest concentration in dry cows. The outcomes of this work improve the accuracy of the metabolic profiles as a tool for assessing the nutritional and health status of dairy cows.Keywords: dairy cow, blood chemistry, metabolic profile RESUMO

show abstract

Supplementation of dairy cows with propylene glycol during the periparturient period: effects on body condition score, milk yield, first estrus post-partum, beta-hydroxybutyrate, non-esterified fatty acids and glucose concentrations

Cited by 9 publications

References 22 publications

Beneficios del Propilenglicol en el Periparto en Cetosis Subclínica y Parámetros Productivos en el Trópico Veracruzano

Beneficios del Propilenglicol en el Periparto en Cetosis Subclínica y Parámetros Productivos en el Trópico Veracruzano

Relationship among blood indicators of lipomobilization and hepatic function during early lactation in high-yielding dairy cows

Reference values for biochemical analytes in Mexican dairy farms: interactions and adjustments between production groups

Contact Info

Product

Resources

About