Alterações fetais induzidas pelo uso de antiinflamatórios durante a gestação

Fonseca, Cláudia Sampaio; Vilória, Marlene Isabel Vargas; Repetti, Cláudia Sampaio Fonseca

doi:10.1590/s0103-84782002000300027

Cited by 3 publications

(3 citation statements)

References 17 publications

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“…Esses medicamentos bloqueiam a síntese de prostaglandinas, podendo constringir o ducto arterioso intrauterino, causar hipertensão pulmonar sustentada no recém-nascido, alterações hemostáticas como a inibição da agregação plaquetária decorrente do uso de salicilatos, além de prolongar a gestação e o trabalho de parto. (36,37) O uso de Ibuprofeno foi ainda relacionado a casos de defeitos glomerulares, acarretando insuficiência renal. (38) Os corticosteroides estão classificados na categoria C da FDA e são considerados mais seguros que os AINES para o tratamento de lesões inflamatórias orais, quando administrados topicamente.…”

Section: Quanto Aos Anti-inflamatóriosunclassified

Desmistificando O Atendimento Odontológico À Gestante: Revisão De Literatura

Bastos

Silva²,

Cardoso

et al. 2014

J Dent Pub H

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Pregnancy is a natural biological process in women’s lives. However, in this period, physiological changes occur in the body of the pregnant woman who also reflects on oral health. Studies reinforce the relationship between the health condition of the oral cavity and the body’s overall health, as well as their implications for the fetus. Thus highlights the importance of Dentistry in health care during pregnancy. However, dental care for pregnant women requires qualification for them to be selected the safest agents. It is necessary, therefore, the formation of dentists able to provide differentiated services for pregnant women, including preventive and curative actions for to promote oral health of the mother and, consequently, the baby. This article has for objective to revise available literature of the odontological treatment during the period of the pregnancy, demystifying dental care pregnant women, in order to make possible clarifications to base the clinical behaviors in scientific evidences.

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Section: Quanto Aos Anti-inflamatóriosunclassified

Desmistificando O Atendimento Odontológico À Gestante: Revisão De Literatura

Bastos

Silva²,

Cardoso

et al. 2014

J Dent Pub H

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“…The glucocorticoids can be applied in the treatment of and endless number of diseases such as: allergies, immunomediated diseases, septal shock, cardiogenic shock, central nerve system traumatism and vertebral column traumas. It has been also used in the therapeutical hormonal reposition, in cases of supra-renal dysfunction and, recently, it has been associated to other medicines to integrate anticancer treatments (Fonseca et al, 2002;Bavaresco et al, 2005).…”

Section: Introductionmentioning

confidence: 99%

Morphological Analysis of Neonates of Rats Treated with Dexamethasone in the Initial Phase of Pregnancy

Júnior¹,

Teixeira

et al. 2008

Int. J. Morphol.

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The glucocorticoid dexamethasone has been largely used due to its anti-inflammatory effect. However, several authors report that the excessive exposition to it during pregnancy may cause a retard in the development in several tissues, mainly: liver, lungs and kidneys. But, the majority of the works are done with the application of dexamethasone in the late periods of pregnancy. Because of the lack of researches that evaluate the effects in the beginning of gestation, this paper aimed at evaluating the effect of dexamethasone administered in the initial phase of pregnancy, over the morphology of neonates rat. It was used 10 albino rats (Rattus norvegicus albinus) aged 90 days from the lineage Wistar. The female were coupled and divided in two groups: Group I -rats not submitted to the dexamethasone application (control); Group II -rats submitted to the dexamethasone application in the first 5 days of pregnancy. The results show that the treatment with dexamethasone in a dosage of 0.8mg/Kg during the 5 first days of pregnancy does not produces a weight and height reduction or malformation in the offspring, it does not cause changes in the development of the liver and kidneys of neonate rats, but it leads to a reduction in the denseness of the interalveolar septa causing a higher distension of the alveoli.

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“…Cada segmento vascular foi examinado uma única vez. Os procedimentos aconteceram em condições não-inflamatórias e inflamatórias (FORTES et al, 1991;FARSKY, SANNOMIYA, GARCIA-LEME, 1995, MARTINEZ et al, 2004.…”

Section: -Medida Do Edema Inflamatóriounclassified

Papel do antidepressivo amitriptilina sobre a resposta inflamatória aguda em ratos

Vismari¹

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Alterações fetais induzidas pelo uso de antiinflamatórios durante a gestação

Cited by 3 publications

References 17 publications

Desmistificando O Atendimento Odontológico À Gestante: Revisão De Literatura

Desmistificando O Atendimento Odontológico À Gestante: Revisão De Literatura

Morphological Analysis of Neonates of Rats Treated with Dexamethasone in the Initial Phase of Pregnancy

Papel do antidepressivo amitriptilina sobre a resposta inflamatória aguda em ratos

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