Two new ent-kaurane diterpenoids from Albizia mollis (Wall.) Boiv

Abstract

Dois novos diterpenos com esqueleto caurano, 3a,16b-17-tri-hidróxi-ent-caurano 3-O-b-Dglucopiranosídeo e ácido 2b,3a-di-hidróxi-ent-caur-15-eno-17-óico 3-O-b-D-glucopiranosídeo, foram isolados das cascas de Albizia mollis (Wall.) Boiv. As estruturas destes dois cauranos foram elucidadas por métodos espectroscópicos uni e bidimensionais e por espectrometria de massas.Two new kaurane diterpenoids, 3a, 16b, 17-trihydroxy-ent-kaurane 3-O-b-D-glucopyranoside and 2b,3a-dihydroxy-ent-kaur-15-en-17-oic acid 3-O-b-D-glucopyranoside, were isolated from the bark of Albizia mollis (Wall.) Boiv. The structures of two new compounds were elucidated by extensive 1D-and 2D-NMR spectroscopic methods in combination with MS experiments.

Terpenoids from Glechoma hederacea var. longituba and their biological activities

“…Also, 1 H and 13 C NMR except for those signals attributed to a glucopyranosyl unit, and optical rotation value of aglycone {[α] −66.5 ( c 0.02, MeOH)} were compared with the reported literature and determined as 3α,12α,16α [ 15 ]. Finally, the ᴅ-glucopyranose unit in 4 was confirmed by GC–MS analysis as described above ( Supporting Information File 1 , Figure S35) [ 10 ], and the coupling constant of anomeric protons at δ H 4.33 ( J = 7.8 Hz) implied β-ᴅ-glucopyranose [ 16 ]. Thus, the structure of compound 4 was identified as ent -kauran-3α,12α,16α-triol 3-O-β-ᴅ-glucopyranoside.…”

Albiziaflavane A: a new flavane from Albizia ferruginea (Mimosoideae)

“…Called 'Evouvous' by Ewondo tribe in the central region of Cameroon, the decoction of its barks mixed with those of Ongokea gore and Piptadeniastrum africanum is used as traditional remedy to cure infertility (Noumi et al 2011). Previously, saponins (Cheng et al 2011), flavonoids (Rao et al 2002) and diterpenoids (Cheng et al 2010) were reported as secondary metabolites identified from different species of Albizia. Therefore, the structural diversity of chemical entities remains an attraction for chemists and biologists.…”

Flavonoids from Albizia procera

“…In traditional Chinese medicine, Albizia members are used for the treatment of insominia, irritability, wounds and as antidysentric, antiseptic and antitubercular 2 . Phytochemical studies carried out on plants of genus Albizia, have revealed them as sources of different groups of natural products, triterpenoid saponins [3][4][5][6][7][8][9][10][11] , diterpenoids 12 , flavonoids [13][14][15][16][17][18][19][20][21][22] , lignans 21,23 , phenolic glycosides 24,25 and pyridineglycoside 26 . As a part of our continuous investigation on secondary metabolites from Albizia species 9,11 , we describe in this report the isolation of five flavonoids from the methanolic extract of A. procera.…”