Essential oil composition of Croton palanostigma Klotzsch from north Brazil

Abstract

Os óleos essenciais das folhas, ramos finos, galhos, cascas do caule e frutos de Croton palanostigma foram analisados por CG e CG-EM. Os componentes principais determinados no óleo das folhas foram linalol (25,4%), (E)-cariofileno (21,0%), metileugenol (17,2%) e b-elemeno (6,0%); no óleo dos ramos finos foram a-pineno (41,4%), limoneno (29,0%), sabineno (11,5%) e b-pineno (5,7%); no óleo dos galhos foram metileugenol (24,1%), (E)-metilisoeugenol (15,3%), a-pineno (11,2%) e (E)-cariofileno (8,5%); no óleo das cascas do caule foram a-pineno (31,6%), metileugenol (25,6%) e (E)-metilisoeugenol (23,7%); e no óleo dos frutos foram linalol (42,7%), metileugenol (16,3%) e b-elemeno (6,4%). Análise estatística mostrou que as folhas e os frutos apresentam significante similaridade entre si, assim como os galhos e as cascas do caule. Adicionalmente, o óleo obtido das cascas do caule possui elevada atividade larvicida sobre Artemia salina (CL 50 , 3,71 ± 0,01 mg mL -1 ).The essential oils of leaves, twigs, branches, trunk bark and fruits of Croton palanostigma were analyzed by GC and GC-MS. The main compounds found in the oil of the leaves were linalool (25.4%), (E)-caryophyllene (21.0%), methyleugenol (17.2%) and b-elemene (6.0%); in the oil of the twigs were a-pinene (41.4%), limonene (29.0%), sabinene (11.5%) and b-pinene (5.7%); in the oil of the branches were methyleugenol (24.1%), (E)-methylisoeugenol (15.3%), a-pinene (11.2%) and (E)-caryophyllene (8.5%); in the oil of the trunk bark were a-pinene (31.6%), methyleugenol (25.6%) and (E)-methylisoeugenol (23.7%); and in the oil of the fruits were linalool (42.7%), methyleugenol (16.3%) and b-elemene (6.4%). Statistical analysis showed that the leaves and fruit, and the branches and trunk bark, have significant similarities between them. In addition, the trunk bark oil has high brine shrimp larvicidal activity (LC 50 , 3.71 ± 0.01 mg mL -1 ).

Chemical constituents and evaluation of cytotoxic and antifungal activity of Lantana camara essential oils

“…Brine shrimp eggs (Maramar) were hatched in artificial salt water (1.0 L of mineral water and 33 g of marine crude NaCl) and used after 24 h applying the modified literature method (Brasil et al, 2009;Parra et al, 2001). Experiments were conducted along with positive control and negative control and different concentrations (0.02; 0.04; 0.06; 0.12; 0.23; 0.25; 0.47; 0.50; 1.0; 5.0; 10.0; 25.0; 50.0 and 100 µg/mL to oil) in a set of three tubes per dose.…”

Chemical composition, antioxidant and topical anti-inflammatory activities of Croton cordiifolius Baill. (Euphorbiaceae)

“…In addition to differences in essential oil constitution among distinct species of the genus Croton, several authors have demonstrated distinct essential oil compositions of different tissues from the same species (Brasil et al, 2009;Lima et al, 2010;Morais et al, 2006;Neves and Camara, 2012). In general, the essential oils of Brazilian Croton species present mono and sesquiterpenes as major components, with the exception of C. zehntneri, in which the phenylpropanoids eugenol and anetol predominate (Craveiro et al, 1981).…”

Análise de terpenóides de espécies de Croton sect. Lamprocroton (Mull. Arg.) Pax (Euphorbiaceae)

“…Compostos considerados bioativos apresentam atividade insetífuga, antimicrobiana, antiviral, antiúlcera, gastroprotetora e antitumoral (Maciel et al, 1998;Fattorusso et al, 2002;Campos et al, 2010). Relatos sobre ocorrência de clerodanos em Croton (principalmente furano-clerodanos) são bastante comuns tendo registro em C. cajucara (Maciel et al, 1998;Grynberg et al, 1999;Souza et al, 2006;Campos et al, 2010), C. draco (Murillo et al, 2001;Deepika-Gupta et al, 2008), C. eluteria (Fattorusso et al, 2002), C lechleri (De Marino et al, 2008), C. membranaceous (Bayor et al, 2009), C. oblongifolius (Youngsa et al, 2007, C. palanostigma (Socorro et al, 2004;Brasil et al, 2009) e C. polyandrus (Araújo-Junior et al, 2005. Nos trabalhos realizados com C. cajucara, um dos diterpenos mais característico é a trans-crotonina, um furano-clerodano bioativo com atividades fungicida (Souza et al, 2006), anti-úlcera (Campos et al, 2010), antitumoral e anti-inflamatória (Grynberg et al, 1999).…”

“…Esta substância já foi descrita em C. sonderianus (Amaral et al, 2004), C. oligandrum (Agnaniet et al, 2006), C. zehntneri, C. nepetaefolius, C. argyrophylloides (Lima et al, 2006;, C. urucurana (Simionatto et al, 2007), C. palanostigma (Brasil et al, 2009) e C.zambesicus (Usman et al, 2009) sendo componente majoritário para C. oligandrum e C. sonderianus. Nas espécies estudadas o cineol foi detectado em altas concentrações em folhas de C. ericoides (24,15% do total identificado), C. dusenii (16,4%), C. linearifolius (26,87%) e C. muellerianus (23,87%) (Tabela 05).…”

“…Possui atividades biológicas e farmacológicas, como imunomoduladora (Ziaei et al, 2010) e antibacteriana (Limberger et al, 2004;Alcantara et al, 2010). Em Croton já foi detectado em C. matourensis (Compagnone et al, 2010), C.zambesicus (Usman et al, 2009), C. palanostigma (Brasil et al, 2009), C. urucurana (Simionatto et al, 2007) C. argyrophylloides (Lima et al, 2006;Morais et al, 2006), C. sonderianus (Lima et al, 2006) e C. oligandrum (Agnaniet et al, 2006). O espatulenol foi detectado no óleo volátil foliar de 70% das espécies estudadas, com destaque para C. catamarcensis, com 43,3% do total identificado (Tabela 05).…”