Hydrolysis of methyl benzoate from Piper arboreum by Naupactus bipes beetle

Ramos, Clécio S.; Kato, Massuo Jorge

doi:10.1590/s0103-50532009000300022

Cited by 10 publications

(7 citation statements)

References 10 publications

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“…7,8 Previous phytochemical studies of the leaf essential oil of P. arboreum revealed as major components the sesquiterpenes δ-cadinene, β-caryophyllene, germacrene D and bicylogermacrene. [9][10][11][12] Biological studies of P. arboreum have shown that their nor-volatile and volatile constituents were active against the fungi Cladosporium sphaerospermum, C. cladosporioides, Candida krusei, C. parapsilosis and Cryptococcus neoformans and protozoan Trypanosoma cruzi.…”

Section: Methylenedioxyphenyl)-7(e)-pentaenoyl]-pyrrolidinementioning

confidence: 99%

“…[3][4][5] In particular, Piper arboreum, a shrub that typically grows to 3 m height, popularly known as long pepper, rosemary-of-Angola or wood-of-Angola, has been used in traditional Brazilian medicine in the form of tea for treatment of rheumatism, bronchitis, colds and flu. 6 Previous chemical investigations carried out on leaves of P. arboreum led to the identification of the amides N- [10-(13,14methylenedioxyphenyl)-7(E),9(Z)pentadienoyl]-pyrrolidine, arboreumine, N- [10-(13,…”

Section: Introductionmentioning

confidence: 99%

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CHEMICAL STUDY AND ANTIMICROBIAL ACTIVITIES OF Piper arboreum (PIPERACEAE)

Nascimento

Araújo

Silva

et al. 2015

J. Chil. Chem. Soc.

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This study evaluated the antifungal and antibacterial activities of the extracts and their fractions, essential oils, and major constituents of Piper arboreum tissues. The chemical compositions of P. arborem tissues and major constituent were identified using GC/MS, 1 H and 13 C NMR. All the botanic material tested proved to be specific bactericidal agents against Staphylococcus aureus, with MBC/MIC = 2, including the amide piperetine, the major compound isolated of P. arboreum for the first time. The essential oil of leaves showed antifungal activity against Microsporum gypseum and Epidermophyton floccosum, with MFC values of 312.5 and 125 µg/mL, respectively.

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Section: Methylenedioxyphenyl)-7(e)-pentaenoyl]-pyrrolidinementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

CHEMICAL STUDY AND ANTIMICROBIAL ACTIVITIES OF Piper arboreum (PIPERACEAE)

Nascimento

Araújo

Silva

et al. 2015

J. Chil. Chem. Soc.

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“…The phytochemistry of the Piperaceae species, mainly of the Piper genus (Parmar et al ., ), has been studied extensively due to the variety of biological activities displayed by their secondary metabolites (Alécio et al ., ; Navickiene et al ., ; Martins et al ., ; Lago et al ., ). Phytochemical studies of Brazilian species of Piperaceae have revealed the presence of amides (Silva et al ., ; Navickiene et al ., ), neolignans (Benevides et al ., ), lignans (Martins et al ., , ; Ramos et al ., ) and prenylated benzoic acid and chromene (Baldoqui et al ., ; Ramos and Kato, ; Ramos et al ., ).…”

Section: Introductionmentioning

confidence: 98%

Secondary Metabolites from the Phloem of Piper solmsianum (Piperaceae) in the Honeydew of Edessa meditabunda

Ramos

Kato

2012

Phytochemical Analysis

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ABSTRACT:Introduction -The phytochemistry of species of the genus Piper has been studied extensively, including Piper solmsianum. However, no studies have addressed the phytochemistry of the sap content of Piper species. Objective -To evaluate the transferring of secondary compounds from the saps of P. solmsianum to the honeydew of Edessa meditabunda. Methodology -The honeydew of E. meditabunda and saps of P. solmsianum were analysed by GC-MS, 1 H-NMR and LC-MS. Results -The lignan (À)-grandisin and the phenylpropanoid (E)-isoelemicin were detected in both saps of P. solmsianum and honeydew of E. meditabunda. Conclusion -Analysis of honeydew secreted by the sap-sucking insect E. meditabunda indicated that (À)-grandisin and (E)-isoelemicin are absorbed from the phloem of Piper solmsianum.

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“…Antibacterial and trypanocidal activities have been reported for Piper arboreum Aub. and this plant is used by traditional communities in Brazil in the form of a decoct against rheumatism, bronchitis, and sexually transmitted diseases (AGRA et al 2007, RAMOS and KATO 2009, REGASINI et al 2009). …”

Section: Introductionmentioning

confidence: 99%

Modulatory antimicrobial activity of piper arboreum extracts

Tintino¹,

Souza²,

Guedes³

et al. 2014

Acta Botanica Croatica

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-The side effects of certain antibiotics have been a recent dilemma in the medical arena. Due this fact, the necessity of natural product discovery could provide important indications against several pharmacological targets and combat many infectious agents. Piper arboreum Aub. (Piperaceae) has been used by Brazilian traditional communities against several illnesses including rheumatism, bronchitis, sexually transmitted diseases and complaints of the urinary tract. Medicinal plants are a source of several remedies used in clinical practice to combat microbial infections. In this study, ethanol extract and fractions of Piper arboreum leaves were used to assay antimicrobial and modulatory activity. The minimum inhibitory concentration (MIC) was determined using microdilution method of ethanol extract and fractions from the leaves of P. arboreum ranging between 8 and 1024 mg mL -1 . The capacity of these natural products to enhance the activity of antibiotic and antifungal drugs was also assayed. In these tests, natural products were combined with drugs. The natural products assayed did not demonstrate any clinically relevant antimicrobial activity (MIC ³ 1024 mg mL -1 ). However, the modulation of antibiotic activity assay observed a synergistic activity of natural products combined with antifungal (such as nystatin and amphotericin B) and antibiotic drugs (such as amikacin, gentamicin and kanamycin). According to these results, these natural products can be an interesting alternative not only to combat infectious diseases caused by bacteria or fungi, but also to combat enhanced resistance of microorganisms to antibiotic and antifungal drugs.

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Hydrolysis of methyl benzoate from Piper arboreum by Naupactus bipes beetle

Cited by 10 publications

References 10 publications

CHEMICAL STUDY AND ANTIMICROBIAL ACTIVITIES OF Piper arboreum (PIPERACEAE)

CHEMICAL STUDY AND ANTIMICROBIAL ACTIVITIES OF Piper arboreum (PIPERACEAE)

Secondary Metabolites from the Phloem of Piper solmsianum (Piperaceae) in the Honeydew of Edessa meditabunda

Modulatory antimicrobial activity of piper arboreum extracts

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