Organotin(IV) esters of 4-maleimido-benzoic acid: synthesis, characterization and in vitro anti-leishmanial effects

Synthesis, spectroscopic characterization, X-ray structures, biological screenings, DNA interaction study and catalytic activity of organotin(IV) 3-(4-flourophenyl)-2-methylacrylic acid derivatives

“…IR spectra were recorded with Thermo Nicolet-6700 FT-IR Spectrophotometer by measuring the absorbance of the samples from 4000 to 400 cm À1 . 1 H and 13 C NMR spectra were recorded at room temperature in CDCl 3 on a Brucker Advance Digital 300 MHz NMR spectrometer (Switzerland). The absorption spectra were recorded on a Shimadzu 1800 UVevis spectrophotometer.…”

“…The organotin(IV) carboxylates have been shown significant antimicrobial properties such as anti-bacterial and anti-fungal [1,2]. The organotin compounds have also received considerable attention as anti-tumor and anti-cancer drugs.…”

Solvent free preparation of N-substituted maleanilic acid

“…The IR spectra were recorded on a Shimadzu FTIR 8300 series spectrometer using KBr pellets. The MHz spectrometer in solutions of CDCl 3 or DMSO-d 6 . The elemental analysis was taken by a Carlo Erba Model NA 500 series analyzer.…”

“…Different solvents can be used, ether [5], acetic acid [6], acetone [7], nitrobenzene [8], chloroform [9] or mixed solvents such as equal volume of ethyl alcohol and water [10]. The reactions were carried out at 0-5 o C [11], room temperature [12,13] or at 70-75 o C [14].…”

Organotin(IV) complexes with 2-acetylpyridine benzoyl hydrazones: antimicrobial activity

“…46,47 Coordination of organotin salts with organic ligands could be an interesting strategy for activity improvement 48 or toxicity reduction. In the present work we demonstrated that coordination of organotin salts to hydrazones might improve the pharmacological profile of both metal and ligands.…”