New biflavonoid and other flavonoids from the leaves of Chimarrhis turbinata and their antioxidant activities

Cardoso, Carmen L.; Silva, Dulce Helena Siqueira; Castro‐Gamboa, Ian; Bolzani, Vanderlan da Silva

doi:10.1590/s0103-50532005000800008

Cited by 21 publications

(17 citation statements)

References 17 publications

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“…Compounds 12-17 were respectively identified as kaempferol-3-O-b-D-glucopyranoside (Kazuma et al, 2003), kaempferol-3-Ob-D-galattopyranoside (Lin et al, 2011), kaempferol-3-O-b-Darabinopyranoside (De Almeida et al, 1998, nicotiflorin (Kazuma et al, 2003), kaempferol-3-robinobioside (Cardoso et al, 2005) and kaempferol-3-neohesperidoside (Kazuma et al, 2003).…”

Section: Isolation and Determination Of Structurementioning

confidence: 99%

Phytochemical investigation and antimicrobial assessment of Bellis sylvestris leaves

Scognamiglio

Buommino

Coretti

et al. 2016

Phytochemistry Letters

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Section: Isolation and Determination Of Structurementioning

confidence: 99%

Phytochemical investigation and antimicrobial assessment of Bellis sylvestris leaves

Scognamiglio

Buommino

Coretti

et al. 2016

Phytochemistry Letters

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“…Os principais ecossistemas de Rubiáceas no Brasil estão na Amazônia, Cerrado e Floresta Atlântica, sendo que um grande número de espécies ainda permanece sem quaisquer estudos químico e biológico (Bolzani et al, 2001). A família é conhecida pela produção de alcaloides, iridóides e antraquinonas (Young et al, 1996), porém, flavonoides também já foram isolados de espécies Rubiaceae (Lopes et al, 2004;Cardoso et al, 2005).…”

Section: Introductionunclassified

Flavonoides e atividade antioxidante em Palicourea rigida Kunth, Rubiaceae

Rosa¹,

Silva²,

Silva³

et al. 2010

Rev. bras. farmacogn.

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RESUMO:A atividade antioxidante, avaliada pelo método DPPH (1,1-difenil-2-picrilidrazila), e o teor em compostos fenólicos totais do extrato bruto metanólico e frações das folhas da espécie Palicourea rigida Kunth, Rubiaceae, foram quantificadas neste trabalho. Apesar da baixa atividade apresentada pelo extrato bruto (500 ppm), a fração acetato de etila apresentou atividade moderada (192 ppm) e o maior teor de fenólicos totais dentre as frações ensaiadas. Assim, a fração acetato de etila foi submetida a procedimentos cromatográficos o que resultou no isolamento dos flavonoides quercetina 3-O-β-D-glicosídeo, quercetina 3-O-soforosídeo e isoraminetina 3-glicosídeo, cujas estruturas foram elucidadas por análise espectroscópica, incluindo RMN (1D e 2D) e comparação com os dados da literatura.Unitermos: Rubiaceae, Palicourea, flavonoides, atividade antioxidante.ABSTRACT: "Flavonoids and antioxidant activity in Palicourea rigida Kunth, Rubiaceae". The antioxidant activity, evaluated by DPPH (1,1-difenil-2-picrilidrazila) method, and the determination of the total phenolic compounds of the crude methanolic extract and fractions of the Palicourea rigida Kunth, Rubiaceae, leaves were quantified in this work. Despite weak activity exhibited by crude extract (500 ppm), the fraction ethyl acetate showed moderate activity (192 ppm), and the largest value for the phenolic compounds among all the assayed fractions. Then, the ethyl acetate fraction was submitted to the chromatography procedures which led to the isolation of the flavonoid quercetin 3-O-D-glicoside, quercetin 3-O-sophoroside and isorhamnetin 3-glicoside, which had the structures elucidated by spectroscopy analysis, including RMN (1D and 2D) and comparison with literature data.

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“…There are no reports regarding the total phenolis and total flavonoid content in Spermacoce species. The Rubiaceae family is known for the production of alkaloids, iridoids, and anthraquinones (YOUNG et al, 1996), and flavonoids have been isolated from species of this family (LOPES et al, 2004, CARDOSO et al, 2005PINTO et al, 2008). Noiarsa et al (2006) identified 18 substances from the aerial parts of Spermacoce laevis Roxb.…”

Section: Resultsmentioning

confidence: 99%

Phytochemistry and larvicidal activity of Spermacoce latifolia Aubl. (Rubiaceae) in the control of Aedes aegypti L. (Culicidae)

et al. 2015

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ABSTRACT:In the search for alternative ways to control Aedes aegypti with minimal environmental impact and in a manner that preserves human health, this study sought to evaluate the larvicidal effect of the invasive and antioxidant Spermacoce latifolia plant by performing a phytochemical study. Phytochemical screenings were done according to characterization reactions and thin layer chromatography. Phenolics compounds content (Folin-Ciocalteu's) and flavonoids (AlCl 3 ) spectrophotometric was performed, and the antioxidant activity was determined by the 2,2-diphenyl-1-picrylhydrazyl (DPPH). The phytochemical results revealed the presence of phenolic, flavonoid, tannin, steroid, free triterpene, coumarin, and alkaloid compounds. The content of total phenols (TPs) (482.7 ± 1.8 mg mgGA g -1 ) and flavonoids (165.4 ± 1.5 mg QE g -1 ) accounted for the antioxidant activity of 150 µg mL -1 methanolic extract. In the proposed bioassays, groups of 25 third-stage larvae were challenged at different concentrations of plant crude extract (1.0, 0.5, 0.25, and 0.1 mg mL -1 ) of weight per volume in four replicates. In multiple concentration tests, the concentrations were selected to range from 0 % to 100 % mortality after 24 hours of contact with the solution. Toxicity was defined as the inhibition or total inactivity of the larvae. It was concluded that the methanol extract had an LC 50 of 0.625 mg mL -1 , indicating its potential use as a larvicide against A. aegypti and linking its activity to its phenolic and flavonoid components.

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New biflavonoid and other flavonoids from the leaves of Chimarrhis turbinata and their antioxidant activities

Cited by 21 publications

References 17 publications

Phytochemical investigation and antimicrobial assessment of Bellis sylvestris leaves

Phytochemical investigation and antimicrobial assessment of Bellis sylvestris leaves

Flavonoides e atividade antioxidante em Palicourea rigida Kunth, Rubiaceae

Phytochemistry and larvicidal activity of Spermacoce latifolia Aubl. (Rubiaceae) in the control of Aedes aegypti L. (Culicidae)

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