Sedative and clinical effects of the pharmacopuncture with xylazine in dogs

Cassu, Renata Navarro; Melchert, Alessandra; Canôa, Jiancarlo Tortoza Bignelli e; Martins, Paula Denise de Oliveira

doi:10.1590/s0102-86502014000100007

Cited by 15 publications

(22 citation statements)

References 29 publications

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“…In dogs, xylazine administered at the Yintang acupuncture point also produces sedation. The degree of sedation was slightly below that produced when administered IM, although the fact that the Yintang point dose was only 1 of 10 of the IM administered dose (1 mg/kg) suggests a potentiation of the drug when given at the acupuncture point (Cassu et al ). Although a degree of potentiation of the sedatives may occur at specific acupuncture points, the dose relationship is probably below 10‐fold.…”

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

“…The administration of drugs into acupuncture points aims to improve drug efficacy and has been employed in people (Cheon et al ) and animals (Luna et al , Takeishi et al , Chang & Namgung , Cassu et al ). In dogs, a low dose of 0·1 mg/kg xylazine at the Yintang point produces relevant sedation (Cassu et al ). We hypothesised that the same dose of the alpha‐2 adrenergic agonist dexmedetomidine (Congdon et al , Carter et al ) administered at the acupuncture point GV20 would provide a higher level of sedation than that produced when administered intramuscularly (IM).…”

Section: Introductionmentioning

confidence: 99%

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Effects of dexmedetomidine administered at acupuncture point GV20 compared to intramuscular route in dogs

Pons

Canfrán

Benito

et al. 2016

J of Small Animal Practice

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Effects of dexmedetomidine administered at acupuncture point GV20 compared to intramuscular route in dogs

Pons

Canfrán

Benito

et al. 2016

J of Small Animal Practice

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“…This method combines the traditional acupoint stimulation with the local delivery of a pharmacological agent and it is supposed to potentiate and prolong the drug effect 12 . Pharmacopuncture has been successfully used to sedate horses 13 and dogs 14 .…”

Section: Introductionmentioning

confidence: 99%

Acupuncture and pharmacopuncture are as effective as morphine or carprofen for postoperative analgesia in bitches undergoing ovariohysterectomy

et al. 2015

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PURPOSE:To investigate the analgesic effect of acupuncture (AP) or micro-dose pharmacopuncture (PA), using carprofen or morphine, in bitches undergoing ovariohysterectomy (OHE). METHODS:Thirty five dogs were randomly assigned to five groups after sedation with acepromazine IM: AP, 0.5 mg.kg -1 of morphine subcutaneously (SC), 4 mg.kg -1 of carprofen SC, and PA with 0.05 mg.kg -1 of morphine or 0.4 mg.kg -1 of carprofen. Anaesthesia was induced with propofol and maintained with isoflurane. Pain was assessed after OHE by a blind observer for 24h, by dynamic visual analogue scale (DIVAS), Glasgow (CMPS-SF), Melbourne (UMPS) and Colorado University pain scale (CSU). Animals reaching 33% of the UMPS score received rescue analgesia with morphine IM. Non parametric data were analysed by Kruskal-Wallis or Friedman tests where applicable, followed by Dunn´s test. Parametric data were analysed by two way ANOVA, followed by Tukey test. RESULTS:There were no differences among groups in number of rescue analgesia. Except for the DIVAS score where animals treated with morphine had the lowest score compared with AP and carprofen, at 1h after surgery, there were no other differences among groups.CONCLUSION: Acupuncture or pharmacopuncture were equally effective as morphine or carprofen to control postoperative pain in bitches undergoing ovariohysterectomy.

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“…A aquapuntura é a injeção de água destilada ou solução de NaCl a 0,9% nos acupuntos (24,25) e a farmacopuntura é a administração de subdoses de fármacos em pontos de AP, o que potencializa o efeito do fármaco, minimiza os efeitos adversos e reduz os custos (26)(27)(28) . O implante de fragmentos de ouro estimula prolongadamente os acupontos, para tratar doenças crônicas, como as síndromes dolorosas ósseas ou osteoartrose (OA) e DCF (29) .…”

Section: Introductionunclassified

Avaliação Do Efeito Da Acupuntura E Técnicas Afins E Perfil Clínico E Epidemiológico De Cães Com Doenças Neurológicas E Osteomusculares Atendidos Em Serviço De Reabilitação Veterinária

Silva

Luna

Joaquim³

et al. 2018

Ciênc. anim. bras.

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ResumoEste estudo retrospectivo avaliou 181 cães com doenças neurológicas e osteomusculares atendidos em um serviço de reabilitação e dor crônica, durante o período de 2013 a 2015. Objetivou-se caracterizar o perfil epidemiológico e clínico dos animais e analisar a eficácia da acupuntura (AP) e terapias afins e respectiva evolução clínica. O diagnóstico baseou-se no exame físico, neurológico, ortopédico e de imagem. As afecções mais prevalentes foram as do sistema nervoso central, sobretudo doença do disco toracolombar e traumas vertebromedulares agudos. Nas enfermidades neurológicas, o tratamento foi considerado eficaz quando os pacientes foram capazes de recuperar a deambulação e para as lesões medulares, quando houve melhora clínica do quadro neurológico avaliado por meio de escores. O sucesso obtido nos quatro segmentos medulares foi de 69,5%. Nas enfermidades osteomusculares, 47% dos cães apresentavam lesões no joelho e 44% displasia coxofemoral (DCF). Adotou-se a escala analógica visual (EAV) de locomoção para definir o sucesso do tratamento nestas doenças, que foi de 52,8%. As técnicas que mais se associaram à AP manual foram, por ordem decrescente, a eletroacupuntura, a ozonioterapia e o LASER. O número de sessões de AP foi em média de 7,6±3,5. Conclui-se que a AP e técnicas afins melhoraram o escore de déficit neurológico nas doenças neurológicas avaliadas quando usadas de forma isolada e quando associadas à medicina convencional. Palavras-chave: eletroacupuntura; disco intervertebral; osteoartrose; dor crônica. AbstractThis retrospective study evaluated the clinical outcome of 181 dogs with neurologic and

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Sedative and clinical effects of the pharmacopuncture with xylazine in dogs

Abstract: Pharmacopuncture with xylazine induced clinically relevant sedative effects in dogs, with the advantage of reduction of undesirable side effects associated with α2-agonists, including bradycardia, cardiac arrhythmias, and emesis.

Cited by 15 publications

References 29 publications

Effects of dexmedetomidine administered at acupuncture point GV20 compared to intramuscular route in dogs

Effects of dexmedetomidine administered at acupuncture point GV20 compared to intramuscular route in dogs

Acupuncture and pharmacopuncture are as effective as morphine or carprofen for postoperative analgesia in bitches undergoing ovariohysterectomy

Avaliação Do Efeito Da Acupuntura E Técnicas Afins E Perfil Clínico E Epidemiológico De Cães Com Doenças Neurológicas E Osteomusculares Atendidos Em Serviço De Reabilitação Veterinária

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