ABSTRACTPurpose: To determine podocyte number and GBM thickness in diabetic rats either under glycemic control or without glycemic control at 6 and 12 months after diabetes induction. Methods: 100 wistar rats weighing 200-300g were divided into 6 groups: Normal group (N6 and N12-25 rats); Diabetic group (D6 and D12-25 rats), diabetic treated group ( DT 6 and DT 12-25 rats) on insulin 1,8-3,0 IU/Kg associated with acarbose (50mg to 100g of food) daily mixed in chow. Alloxan was injected intravenously in a dose…
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