2006
DOI: 10.1590/s0102-86502006000700020
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Citizenship and experimental research

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“…Animal experimentation should follow the recommendations of the "3 Rs", proposed by Russell and Burch (1959): reduction (reduced number of animals under experimentation), refinement (relief of pain and stress, and increasing the welfare of animals under experimentation) and replacement (replacement of animals in research for simulators) [4]. In an editorial, Goldenberg (2007) also highlights three important principles in animal experimentation: gain experience does not mean to cause injury, the practice of art and science must come together and publishing of the experimental study, because nonpublished knowledge is a lack of knowledge [5].…”
mentioning
confidence: 99%
“…Animal experimentation should follow the recommendations of the "3 Rs", proposed by Russell and Burch (1959): reduction (reduced number of animals under experimentation), refinement (relief of pain and stress, and increasing the welfare of animals under experimentation) and replacement (replacement of animals in research for simulators) [4]. In an editorial, Goldenberg (2007) also highlights three important principles in animal experimentation: gain experience does not mean to cause injury, the practice of art and science must come together and publishing of the experimental study, because nonpublished knowledge is a lack of knowledge [5].…”
mentioning
confidence: 99%