Infection on the meshes implantation area in the abdominal wall of rats with induced bacterial peritonitis

BackgroundThe use of alloplastic meshes has been historically contra-indicated in patients with infection.AimTo evaluate the use of polypropylene meshes in the treatment of abdominal wall defects in rats with peritonitis.MethodsTwenty Wistar female rats were divided into two groups: induction of peritonitis (test group) and without peritonitis (control group). An abdominal wall defect was created in all animals, and polypropylene mesh was applied. The evaluation of the tensile strength of the mesh was carried out using tensiometer and microscopic analysis of the healing area was done.ResultsMore adhesion of the mesh to the rat abdominal wall was observed in test group. The histopathological analyses showed prevalence of moderate to accentuated granulation tissue in both groups, without significant differences.ConclusionThe use of the mesh coverage on abdominal wall defects of rats with induced peritonitis did not show worse results than its use in healthy animals, nor was its integration to the resident tissue any worse.

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Ventral abdominal wall defect correction in rats with contaminated meshes

Varella

Czeczko

Prestes

et al. 2016

Acta Cir. Bras.

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Infection on the meshes implantation area in the abdominal wall of rats with induced bacterial peritonitis

Abstract: The experimental model used was effective, producing 100% of peritonitis. The incidence of bacterial growth on the implanted polypropylene meshes was 83% in 24 hours, decreasing with the time.

Cited by 5 publications

References 18 publications

Multifunctional prosthetic polyester-based hybrid mesh for repairing of abdominal wall hernias and defects

Multifunctional prosthetic polyester-based hybrid mesh for repairing of abdominal wall hernias and defects

Use of alloplastic meshes in abdominal wounds of rats with induced peritonitis

Ventral abdominal wall defect correction in rats with contaminated meshes

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