Efeito de agentes anti-hipertensivos sobre as células estreladas durante a regeneração hepática em ratos

Ramalho, F.S.; Ramalho, L.N.Z.; Zucoloto, Sérgio; Castro‐e‐Silva, Orlando; Corrêa, Fernando M.A.

doi:10.1590/s0102-86502000000600028

Cited by 1 publication

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“…In that context, there is intensive fibroblastic and myofibroblast proliferation. Myofibroblasts are responsible for wound contraction as long as they synthesize collagen fibers and allow a retraction in the damage edges promoting the final closing of the lesion by its smooth muscle alpha actin contractile filaments (Figure 4) (Paganela et al, 2009;Sarandy, 2007;Ramalho et al, 2003). In the transition from proliferative to remodeling phase, keratinocytes and fibroblasts migration becomes intensive which results in the re-epithelization and neo-collagenesis, respectively (Figures 5 and 6).…”

Section: Resultsmentioning

confidence: 99%

Tissue repair under the influence of plasma jet and other biomodulator therapies - state of the art

Cerqueira

Dantas

Souza

et al. 2022

RSD

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Tissue repair process consists in a complex and dynamic event straightly linked to tissues self-regeneration capability. In that context, it may also occur total or partial replacement of the original tissues through an extracellular matrix with significant collagen and elastin expression that results in fibroplasia. Aiming to optimizing the repair, it has been used some resources able to biomodulate the action of different kinds of tissue cells such as laser photobiomodulation (LP), light emitting diodes (LEDs), ozone therapy and plasma jet. This narrative literature review aims to describe the different phases of tissue repair and discuss about biomodulator therapies commonly applied to stimulate that process. Manuscripts discussing the proposal theme, which have been fully available were selected from Pubmed, Embase, Cochrane and Scielo database. The manuscripts must be written in English or Portuguese language, according to the exclusion and inclusion criteria designed for that study. Sixty manuscripts were selected. It may be noticed that biomodulator therapies have been used in health areas. However, studies evaluating the influence of plasma jet on tissue repair are still scarce. Preliminary results from such studies suggest that plasma jet therapy may perform important antiinflammatory, analgesic and biostimulating effects.

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Section: Resultsmentioning

confidence: 99%