“…13 Heart transplantation is still the best option, through providing increased quality of life and longer survival. 14,15 This procedure has been presenting results of greater consistency, thanks to improvements and adaptations in recipient selection, donor maintenance, new immunosuppressant drugs, advances in diagnosing rejection and experience of post-transplant management. 9,16 Nonetheless, transplantation presents many limitations, including the need for immunosuppressive therapy, high costs, donor shortage, high mortality in the waiting lists and very rigid indication criteria.…”