Caso 5/2006: operação de Rastelli com homoenxerto pulmonar decelularizado

Croti, Ulisses Alexandre; Braile, Domingo Marcolino; Kozak, Ana Carolina Leiroz Ferreiro Botelho Maisano; Beani, Lilian

doi:10.1590/s0102-76382006000300018

Cited by 1 publication

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“…Tissue engineering valved conduits is a perfect technology assumption, which is supposed to achieve lifelong functional requirements through in-vitro cell seeding and culturing, bioprinting, or in-vivo regeneration approaches (65). It seems to be more feasible to induce remodeling in vivo based on the cellfree natural scaffolds or synthetic biodegradable materials, other than in-vitro cell culturing (66).…”

Section: Other Conduitsmentioning

confidence: 99%

Conduits for Right Ventricular Outflow Tract Reconstruction in Infants and Young Children

et al. 2021

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Purpose of Review: Right ventricular outflow tract (RVOT) reconstruction remains a challenge due to the lack of an ideal conduit. Data and experience are accumulating with each passing day. Therefore, it is necessary to review this topic from time to time. This is a 2021 update review focused on the history, evolution, and current situation of small-sized conduits (≤ 16 mm) for RVOT reconstruction in infants and young children.Recent Findings: Currently, the available small-sized (≤16 mm) conduits can meet most clinical needs. Homograft is still a reliable choice for infants and young children validated by a half-century clinical experience. As an alternative material, bovine jugular vein conduit (BJVC) has at least comparable durability with that of homograft. The performance of expanded polytetrafluoroethylene (ePTFE) is amazing in RVOT position according to limited published data. The past century has witnessed much progress in the materials for RVOT reconstruction. However, lack of growth potential is the dilemma for small-sized conduits. Tissue-engineering based on cell-free scaffolds is the most promising technology to obtain the ideal conduit.Summary: No conduit has proved to have lifelong durability in RVOT position. We are far from the ideal, but we are not in a state of emergency. In-depth clinical research as well as innovation in material science are needed to help improve the durability of the conduits used in infants and young children.

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Section: Other Conduitsmentioning

confidence: 99%