Aortic valve replacement using bovine pericardial bioprostheses: 12 years of experience

Braile, Domingo Marcolino; Leal, João Carlos Ferreira; Godoy, Moacir Fernandes de; Braile, M.C.V.; Neto, Alfredo de Paula

doi:10.1590/s0102-76382003000300005

Cited by 6 publications

(1 citation statement)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Despite the small number of cases reported in the literature, some authors suggest that aortic valve replacement would be the best choice, considering the poor long-term results while preserving the valve in this context [4], compared to the consistent results of aortic valve replacement by bovine pericardium bioprosthesis [5,6]. However, there are reports showing acceptable results using the repair and preservation of the valve [7], although the safety of this technique is not known.…”

Section: Discussionmentioning

confidence: 99%

Insuficiência aórtica aguda por avulsão de comissura valvar aórtica

Cunha¹,

Santos²,

Atik³

et al. 2012

Rev Bras Cir Cardiovasc

View full text Add to dashboard Cite

A 66-year-old male patient, prior hypertension, a history of orthopnea, palpitations and chest pain of sudden onset, which was diagnosed as spontaneous avulsion of aortic valve commissure and consequent aortic insufficiency progressing to acute left heart failure refractory to medical treatment. The patient underwent early surgical replacement of the aortic valve by a bioprosthesis, and presented satisfactory postoperative course. Currently, four years after the event, he is still in attendance in functional class I.Descriptors: Aortic valve insufficiency. Heart valve diseases. Cardiac surgical procedures. RBCCV 44205-1365

show abstract

Section: Discussionmentioning

confidence: 99%

Insuficiência aórtica aguda por avulsão de comissura valvar aórtica

Cunha¹,

Santos²,

Atik³

et al. 2012

Rev Bras Cir Cardiovasc

View full text Add to dashboard Cite

show abstract

“Less Stented” Bovine Pericardial Xenograft: A New Concept

et al. 2006

View full text Add to dashboard Cite

The in vitro hemodynamic behavior of a bovine pericardium xenograft with discontinuity of the annular support, named the "Less Stented" bovine pericardial xenograft, was analyzed. A "Less Stented" bovine pericardial xenograft consisting of a glutaraldehyde-treated bovine pericardium prosthesis manufactured in Braile Biomédica Ltd, São José do Rio Preto, São Paulo, Brazil, was used according to the same protocols of the stented bioprosthesis manufacturer. Bovine pericardial xenografts were tested in a pulse simulator and analyzed in a cardiac simulator, with respect to the transvalvular gradient, regurgitant fraction and leakage volume, discharge coefficient, performance, and efficiency index. Analyses were performed by Pearson's correlation test and simple linear regression. The transvalvular gradients ranged between 6.37 and 11.62 mm Hg with a mean flow between 4.39 and 7.96 L/min, giving a good correlation (0.8291) on the regression curve with an increase in flow. The regurgitant fraction ranged between 10.95 and 17.94% and leakage volume between 4.49 and 7.87%. The discharge coefficient, performance, and efficiency index showed favorable behavior with the flow increase, with good correlation coefficient (0.9385, 0.9332, and 0.9024, respectively). The initial results of the "Less Stented" bovine pericardial xenograft size 25 analyses demonstrated a satisfactory in vitro performance. Evaluations of the hemodynamic performance of small size "Less Stented" bovine pericardial xenograft should be made to clarify the biological behavior of this new xenograft.

show abstract

Novo conceito de Bioprótese: bioprótese com descontinuidade do anel de sustentação (Less Stented)®

Pomerantzeff¹,

Brandão²,

Braile³

et al. 2004

Rev Bras Cir Cardiovasc

Self Cite

View full text Add to dashboard Cite

Objective: To study a bioprosthesis with discontinuation of the annular support, named the "Less Stented     " bioprosthesis. The Phase 1 objective was an "in vitro" study, during which the hemodynamic characteristics of the prosthesis were analyzed. Phase 2 of this study consisted of an initial clinical implant protocol. Methods: The "Less Stented" bioprosthesis consists of a glutaraldehyde treated bovine pericardium prosthesis manufactured by Braile Biomedica Ltda, São José do Rio Preto, São Paulo, Brazil, using the same manufacturing protocols as the stented bioprostheses but with discontinuation of the annular support. Bioprostheses were tested in a pulse simulator system and analyzed in a cardiac simulator with respect to the transvalvular gradient, regurgitant fraction and leakage volume, discharge coefficient, performance and efficiency index. The two patients of the clinical protocol were analyzed according to the functional class (NYHA), an echocardiographic study and magnetic resonance, in both the pre-and postoperative periods. Results: The transvalvular gradients ranged from 6.37 to 11.62 mmHg with a mean flow between 4.39 and 7.96 L/min, giving a good correlation (0.8291) on the regression curve with the increase in flow. The regurgitant fraction ranged between 10.95% and 17.94% and leakage volume between 4.49% and 7.87%. The discharge coefficient, performance and efficiency index showed favorable behavior with the increase in flow, with good coefficient correlations for all three variables (0.9385, 0.9332 and 0.9024, respectively). The two patients submitted to "Less Stented    " bioprostheses implant presented with good clinical evolutions. Conclusions: "Less-Stented    " bioprostheses may represent a new alternative to aortic valve replacement. Descriptors: Bioprostheses. Heat valve prosthesis. Aortic valve, surgery. Resumo Objetivo: Estudar bioprótese com descontinuidade do anel de sustentação, a bioprótese "Less Stented      ". O objetivo da fase 1 do trabalho foi o seu estudo "in vitro", onde foram avaliadas as características hemodinâmicas. O objetivo da fase 2 é relatar a experiência clínica inicial. Método: As biopróteses foram confeccionadas e avaliadas laboratorialmente na Braile Biomédica, em São José do Rio Preto, São Paulo. São próteses de pericárdio bovino, tratadas Novo conceito de Bioprótese: bioprótese com descontinuidade do anel de sustentação(Less Stented) ®New concept of Bioprostheses: a biosprothesis with discontinuation of the annular suport, the "Less Stented" POMERANTZEFF, PMA ET AL -New concept of Bioprostheses: a biosprothesis with discontinuation of the annular suport, the "Less Stented"

show abstract

Aortic valve replacement using bovine pericardial bioprostheses: 12 years of experience

Cited by 6 publications

References 19 publications

Insuficiência aórtica aguda por avulsão de comissura valvar aórtica

Insuficiência aórtica aguda por avulsão de comissura valvar aórtica

“Less Stented” Bovine Pericardial Xenograft: A New Concept

Novo conceito de Bioprótese: bioprótese com descontinuidade do anel de sustentação (Less Stented)®

Contact Info

Product

Resources

About