Avaliação do desempenho hemodinâmico do dispositivo de assistência ventricular InCor como substituto do coração esquerdo

Benício, Anderson; Moreira, Luíz Felipe Pinho; Hayashida, Sergio A.; Cestari, Idágene Aparecida; Leirner, Adolfo A.; Stolf, Noedir Antônio Groppo; Jatene, Adib

doi:10.1590/s0102-76381999000300008

Cited by 7 publications

(5 citation statements)

References 9 publications

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“…The ventricular assist device employed in this study is a nationally-developed paracorporeal device that has its clinical application linked to a trial protocol approved after several 'in vitro' studies and its use in animal experimentation [19,20]. In this study, the maintenance of patients for periods that varied from 11 to 31 days without complications related to the circulatory assist system itself is promising for its routine use.…”

Section: Commentsmentioning

confidence: 99%

Perspectivas da evolução clínica de pacientes com cardiomiopatia chagásica listados em prioridade para o transplante cardíaco

Moreira¹,

Galantier²,

Benício³

et al. 2005

Rev Bras Cir Cardiovasc

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RBCCV 44205-757Perspectivas da evolução clínica de pacientes com cardiomiopatia chagásica listados em prioridade para o transplante cardíaco Clinical perspectives of patients with Chagas cardiomyopathy listed as high priority for heart transplantation Abstract Introduction: Heart failure deterioration is responsible for elevated mortality rates in the heart transplantation waiting lists. In Chagas cardiomyopathy, the presence of biventricular dysfunction increases the severity of this complication.Method: We studied 141 patients with cardiogenic shock, listed in priority for heart transplantation. Forty six patients presented Chagas cardiomyopathy and 95 other cardiomyopathies. Heart failure deterioration was treated with intravenous inotropic drugs and intra-aortic balloon pump insertion. Five patients with Chagas disease underwent paracorporeal left ventricular assist device implantation.Results: During a mean follow-up of 2.8 months, 58 (41.1%) of the 141 patients were transplanted, while 73 (53.7%) died and 10 were removed from the waiting list. The mortality of chagasic and non chagasic patients were 45.6% and 54.7%, respectively. Otherwise, the median survival expectation of patients with Chagas disease, without the heart transplantation performance, was only 1.5 months, and these patients presented a relative risk of mortality of 1.6 in relation to patients with other cardiomyopathies (p<0.05). The five patients submitted to left ventricular assist device implantation were maintained under support for a mean of 22 days. Two of them were transplanted, two died due to multiple organ failure and one still under circulatory support. None of these patients presented right ventricular dysfunction and there were no device related complications.Conclusion: The evolution of heart failure deterioration seems to be rapid in patients with Chagas cardiomyopathy. Therefore, it is important the precocious indication of mechanical circulatory support as a bridge to heart transplantation in these patients.Descriptors: Chagas cardiomyopathy. Shock, cardiogenic. Heart transplantation. Heart assist devices. 262 MOREIRA, LFP ET AL -Clinical perspectives of patients with Chagas cardiomyopathy listed as high priority for heart transplantation

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Section: Commentsmentioning

confidence: 99%

Perspectivas da evolução clínica de pacientes com cardiomiopatia chagásica listados em prioridade para o transplante cardíaco

Moreira¹,

Galantier²,

Benício³

et al. 2005

Rev Bras Cir Cardiovasc

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“…The Heart Institute (InCor-FMUSP), developed and concluded an artificial ventricle project having already clinically applied in patients in the waiting phase for donors [1][2][3][4], however, it is not available because it is only indiscriminately being applied in cases isolates. Dante Pazzanese Institute of Cardiology (IDPC-SP) also concluded a spiral blood pump project [5,6] and Kubrusly et al [7] published an article on intraventricular assist device of axial flow, which still was in experimental phase.…”

Section: Introductionmentioning

confidence: 99%

Estudo experimental da aplicação do ventrículo artificial eletromecânico pulsátil implantável

Dinkhuysen¹,

Andrade²,

Conteras³

et al. 2011

Rev Bras Cir Cardiovasc

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“…In Brazil, the experience with the use of mechanical circulatory-assist devices in the treatment of cardiogenic shock is small and comprises only isolated case reports 12,13 or experiments related to the development of new devices [14][15][16] . In parallel, the life expectancy of the patients in this situation, particularly those of Chagasic etiology, is very limited 17 , requiring the implementation of regular programs of mechanical circulatory assistance, especially as a bridge to cardiac transplantation.…”

Section: Introductionmentioning

confidence: 99%

“…Despite the external positioning, it provides relative mobility to the patient, being capable of maintaining the circulation for longer periods. During its assessment in an experimental calf model, it showed good hemodynamic performance and the capacity to adequately substitute left ventricular function 14 . Experimental studies have demonstrated the possibility of maintaining this device implanted in parallel with circulation for several weeks 18 and its first clinical use was carried out in 1993, with a favorable result 13 .…”

Section: Introductionmentioning

confidence: 99%

Desempenho hemodinâmico e resposta inflamatória durante o uso do DAV-InCor como ponte para o transplante

Galantier¹,

Moreira²,

Benício³

et al. 2008

Arq. Bras. Cardiol.

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SummaryBackground: Cardiac transplantation faces the serious problem of lack of donors and it is estimated that 20 to 40% of the patients die while waiting for heart transplantation. For these patients, the use of mechanical circulatory assist devices is the only choice of survival while waiting for a donor. In Brazil, the experience with mechanical circulatory support is limited and there is no regular program regarding the use of these devices as a bridge to heart transplantation.

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Avaliação do desempenho hemodinâmico do dispositivo de assistência ventricular InCor como substituto do coração esquerdo

Abstract: Avaliação do desempenho hemodinâmico do dispositivo de assistência ventricular InCor como substituto do coração esquerdo

Cited by 7 publications

References 9 publications

Perspectivas da evolução clínica de pacientes com cardiomiopatia chagásica listados em prioridade para o transplante cardíaco

Perspectivas da evolução clínica de pacientes com cardiomiopatia chagásica listados em prioridade para o transplante cardíaco

Estudo experimental da aplicação do ventrículo artificial eletromecânico pulsátil implantável

Desempenho hemodinâmico e resposta inflamatória durante o uso do DAV-InCor como ponte para o transplante

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