Objective. The present study objective is to determine the explanatory value of psychosocial adjustment resources on life satisfaction in a group of high school graduates. Method. The sample was selected from a total of 117271 young people, who in 2016, graduated from upper secondary education in the municipalities of Navojoa, Hermosillo and Ciudad Obregón, in Mexico. The fi nal sample consisted of 2237 participants, who responded to four measures of psychosocial adjustment (self-concept, locus of control, coping and orientation to success) and a questionnaire of life satisfaction. For the data analysis, a linear regression model was performed. Results. The fi nal regression model suggests that the positive self-concept (β = 0.62) and positive coping (β = 0.14) predict life satisfaction in the high school graduates (R 2 = 0.63). Conclusion. The self-concept is the variable with the greatest determination about life satisfaction in the sample. On the other hand, the adjustment profi le of adolescents fundamentally depends on their self-concept, their locus of control and their ways of facing the problems, which should be considered in order to promote an adequate transition from high school to higher education.