Gochnatia polymorpha: macro- and microscopic identification of leaf and stem for pharmacognostic quality control

Youssef, Juliana; Döll-Boscardin, Patrícia Mathias; Farago, Paulo Vítor; Duarte, Márcia do Rocio; Budel, Jane Manfron

doi:10.1590/s0102-695x2013005000054

Cited by 8 publications

(3 citation statements)

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“…In this work, morphology was used as classification criteria. Glandular trichomes have been described for Asteraceae family (Milan et al 2006;Souza et al 2011;Youssef et al 2013;Pereira et al 2014). C. serrata showed two types of glandular trichomes, capitate-stalked and capitate-sessile.…”

Section: Discussionmentioning

confidence: 99%

“…Several genera of Asteraceae can present anomocytic (predominantly) and anisocytic stomata as observed in Gochnatia (Youssef et al 2013), Lucilia , Baccharis (Oliveira et al 2011;Souza et al 2011), Mikania, Porophyllum and Vernonia (Milan et al 2006). The studied species revealed both the anomocytic and anisocytic stomata only in the abaxial surface.…”

Section: Discussionmentioning

confidence: 99%

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Anatomical Characters of Leave and Stem of Calea serrata Less., Asteraceae

Camilotti

Biu

Farago

et al. 2014

Braz. arch. biol. technol.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Anatomical Characters of Leave and Stem of Calea serrata Less., Asteraceae

Camilotti

Biu

Farago

et al. 2014

Braz. arch. biol. technol.

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“…Among the great diversity of plants, there is the Astereaceae family, which includes different Calea genera (Youssef et al, 2013). The genus Calea consists of 110 species that are distributed from northern to southern Brazil (Moura and Roque, 2014).…”

Section: Introductionmentioning

confidence: 99%

Phytochemical investigation, antinociceptive activity and cytotoxicity of crude extracts of Calea uniflora Less.

Rodrigues-Torres¹,

Machado²,

Ramos³

et al. 2016

J. Med. Plants Res.

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Calea uniflora Less. is a medicinal plant used in the treatment of inflammation and haematomas in southern Brazil. The aim of this study was to investigate the antinociceptive effects and cytotoxicity of C. uniflora. Regarding phytochemical evaluation, the crude extracts of plant were analysed by highperformance liquid chromatography (HPLC). Antinociceptive activities utilised models on chemical and thermal stimuli in vivo. To evaluate cytotoxic activity, the 3-(4,5-dimethylthiazol-2-yl) 2,5-diphenyltetrazolium bromide method (MTT test) was utilised in vitro. Phytochemical analyses verified the presence of flavonoids and sesquiterpenes. Regarding antinociceptive activity, the models produced significant results that correspond to chemical at doses of 100 and 300 mg/kg of the crude extract as compared to the control groups, respectively. The rota rod model showed satisfactory results, since the extract did not cause motor incoordination and sedation in this experiment. In the in vitro cytotoxic tests, the crude extracts and ethyl acetate and butanolic fractions produced IC 50 values greater than 58 µg/mL with the HaCaT lineage and 48 µg/mL with the B16-F1 lineage; thus, these values did not produce cytotoxic effects. According to these results, flavonoids and alkaloids were found in C. uniflora extracts. Pharmacological activities were also detected as reported by the local population that uses this plant in traditional medicine, especially antinociceptive and cytotoxic activities.

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