Evaluation of reversible contraceptive potential of Cordia dichotoma leaves extract

The genus Cordia: botanists, ethno, chemical and pharmacological aspects

“…At a dose of 1000 mg/kg, no implantation sites were observed, but there were some behavioral changes such as general weakness, as noted by slow and uncoordinated movements. At 800 mg/kg, pregnancy was blocked 100% and there were no alterations in behavior (Bhattacharya and Saha, 2013).…”

“…The leaves and stem of C. curassavica are used for various superficial inflammatory processes in wound areas and general inflammations and also as an analgesic for menstrual colic (Bayeux et al, 2002). The leaves of C. flavescens are used as an analgesic for postpartum pain (Bhattacharya and Saha, 2013). Ethnopharmacological studies are important for initiating pharmacological tests aimed at proving the possible applications of natural products from plants (Matias et al, 2013b).…”

“…E.F.F. Matias et al / Revista Brasileira de Farmacognosia xxx (2015) xxx-xxx (Al-Musayeib et al, 2011;Bayeux et al, 2002;Bhattacharya and Saha, 2013;Caparroz-Assef et al, 2008;Cardozo et al, 2008;Costa et al, 2008;Matias et al, 2010bMatias et al, , 2013aPanghal et al, 2011b;Salazar-Aranda et al, 2011;Ticli et al, 2005).…”

Traditional uses, phytochemistry and pharmacology of the medicinal species of the genusCordia(Boraginaceae)

“…The result of the study did not show any toxic signs except hypoactivity in mice at a dose of 3.5 g/kg, and the LD 50 value of the extract was found to be 5.5 g/kg after oral administration. [202] The hydroalcoholic leaf extract of C. ecalyculata (500, 100 and 2000 mg/kg) was evaluated for genotoxicity and cytotoxicity using two short-duration tests (the comet assay and micronucleus test). In the peripheral blood, the extract demonstrated a weak clastogenic effect but did not show cytotoxic or clastogenic activity against PCEs in the bone marrow for the treatment of 24 h and 15 days.…”

Anatomical study of vegetative parts and Powder microscopy of Cordia myxa L. (Boraginaceae) in Iraq

“…All the parts of this plant used as popular medicine when the stem bark of Cordia is used in traditional medicine for the treatment of gastric and respiratory disturbances [5]. In the Alagoas State, the leaves and flowers are used as treatment of hemorrhaging, throat infections and cold [6], also the leaves and roots of Cordia are used in folk medicine for digestive disturbances, rheumatism and as a generaltonic [7], besides the treatment of symptoms of menstrual colic and dyspepsia [8]- [9]- [10], so the leaves and stem of Cordia are used for various superficial inflammatory processes in wound areas and general inflammations and also as an analgesic for menstrual colic [11]. The survey concluded that no anatomical studies were carried on this genus in Iraq or abroad.…”