Systemic and reproductive toxicity induced by Parkia platycephala ethanolic extract in female Wistar rats

Costa, B. A.; Oliveira, Jamylla Mirck Guerra de; Sales, P. A. B.; Lira, Silvéria Regina de Sousa; Silva, Silvana M.M. de S.; Costa, Luciana Muratori; Muratori, Maria Christina Sanches; Costa, Amilton Paulo Raposo

doi:10.1590/s0102-695x2013000600009

Cited by 5 publications

(4 citation statements)

References 9 publications

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“…These maternal systemic toxicity findings indicate that the prenatal oral administration of herbal tea of M. stenopetala and M. spicata leaves may not induce significant effects on the serum biochemistry and gross necropsy of pregnant rats at the studied dose levels. Similar results were observed with previous prenatal developmental toxicity studies of extracts of Orthosiphon stamineus leaves [53] , Parkia platycephala leaves [54] , and Salacia lehmbachii root [52] , which revealed that oral administration of the extracts at different doses during the days 5–19 of gestation produced no significant systemic toxicity effects in rats.…”

Section: Discussionsupporting

confidence: 90%

Prenatal developmental toxicity study of herbal tea of Moringa stenopetala and Mentha spicata leaves formulation in Wistar rats

et al. 2022

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Section: Discussionsupporting

confidence: 90%

Prenatal developmental toxicity study of herbal tea of Moringa stenopetala and Mentha spicata leaves formulation in Wistar rats

et al. 2022

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“…Alkaloids, glycosides, saponins, and tannins are present in the whole plant of P. clappertoniana [ 31 ]. Phytochemical analysis of the leaves of P. platycephala revealed the presence of phenols, terpenoids, flavonoids [ 53 ], tannins and saponins [ 54 ]. Furthermore, flavonoids, alkaloids, phenols, and terpenoids were reported to be present in all parts of P. speciosa plant [ 37 ].…”

Section: Phytochemistry Of Genus Parkiamentioning

confidence: 99%

“…P. platycephala leaves at 1000 mg/kg on the other hand, caused decreases in body mass, food and water consumption in rats. It also shortened the proestrus and prolonged diestrus phases, as well as reduced uterine weight, suggestive of possible alterations on hormonal levels, but no obvious toxicity on other organs [ 53 ]. Oral administration of the leaves of P. speciosa for 14 days showed no significant histopathological toxicity or mortality in rats at up to 5000 mg/kg [ 198 ].…”

Section: Toxicitymentioning

confidence: 99%

Genus Parkia: Phytochemical, Medicinal Uses, and Pharmacological Properties

Saleh

Jalil

Zainalabidin

et al. 2021

IJMS

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The genus Parkia (Fabaceae, Subfamily, Mimosoideae) comprises about 34 species of mostly evergreen trees widely distributed across neotropics, Asia, and Africa. This review aims to provide an overview of the current status of the species from the genus Parkia in terms of its relationship between its phytochemistry and medical uses. Comprehensive information on Parkia species was retrieved from electronic databases, which were Web of Science, ScienceDirect, PubMed, and Google Scholar. This review identified nine species from genus Parkia with properties of medicinal use. They are used traditionally to treat several ailments, such as diabetes, diarrhea, wounds, hypertension, cough, chronic piles, conjunctivitis, and measles. The most common species studied are P. biglobosa, P. speciosa, P. javanica, P. bicolor, P. biglandulosa, P. filicoidea, and P. clappertoniana. A considerable number of secondary metabolites, such as terpenoids, phenolic acids, flavonoids (aglycone and glycosides), and numerous volatile compounds have been identified in this genus, which are responsible for their diverse pharmacological activities. Their extracts, pure compounds and seed lectins have been reported for their anticancer, antimicrobial, antihypertensive, antiulcer, antidiabetic, anti-inflammatory, antioxidant, antimalarial, hepatoprotective, and antidiarrheal activities. The information gathered in this review might be of help for future studies in terms of the current knowledge on the link between the phytochemical components and medicinal uses. This could facilitate more discoveries on its potentials particularly in the pharmacological characteristics and potential to be developed into modern medicines.

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“…Coriander (Coriandrum sativum L.), is a plant species belonging to the Apiaceae family, it is a herbaceous and annual plant. It is a seasoning plant widely used in Brazil, mainly as seasoning for fish, meat, sauces and salads (COSTA, 2002).…”

Section: Introductionmentioning

confidence: 99%

Different Types of Light in the Production of Coriander Seedlings

Rocha¹,

Girelli²,

Canova³

et al. 2023

IJBNS

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The objective of this work was to evaluate different types of light in the production of coriander seedlings cultivar Verdão. The seeds were sown in trays containing Carolina Soil® vegetal substrate and maintained in a growth chamber with a 16-hour photoperiod and a light intensity of 25 µmol m -2 s -1 . The treatments were blue LEDs, green LEDs, red LEDs and a control consisting of no artificial light. The experimental design used was entirely randomized with ten repetitions. After 30 days, plant height, number of leaves, root length, and fresh mass of the aerial and root parts were evaluated. The data obtained were submitted to variance analysis, and the means were compared using the Tukey test at 5% probability of error. The seedlings grown under the blue LEDs showed a greater number of leaves (24 leaves) than those kept under green LEDs. The greatest root length (10.65 cm) was obtained under the blue LEDS, followed by the red LED (8.45 cm). Regarding the fresh mass of the aerial part, the highest averages were obtained under the blue LEDs and red LEDs, which did not differ from each other. As for the root fresh mass variable, the highest averages were obtained under the blue LED and the red LED. The height of the coriander seedlings was not influenced by the type of light.

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Systemic and reproductive toxicity induced by Parkia platycephala ethanolic extract in female Wistar rats

Cited by 5 publications

References 9 publications

Prenatal developmental toxicity study of herbal tea of Moringa stenopetala and Mentha spicata leaves formulation in Wistar rats

Prenatal developmental toxicity study of herbal tea of Moringa stenopetala and Mentha spicata leaves formulation in Wistar rats

Genus Parkia: Phytochemical, Medicinal Uses, and Pharmacological Properties

Different Types of Light in the Production of Coriander Seedlings

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