Chemical composition, antischistosomal and cytotoxic effects of the essential oil of Lavandula angustifolia grown in Southeastern Brazil

Mantovani, André Luis Lembi; Vieira, Geovana P.G.; Cunha, Wilson Roberto; Groppo, Milton; Santos, Raquel; Rodrigues, Vanderlei; Magalhães, Lizandra G.; Crotti, Antônio Eduardo Miller

doi:10.1590/s0102-695x2013000600004

Cited by 30 publications

(33 citation statements)

References 41 publications

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“…This leads in some case to a huge difference between chemotype of the same plants collected in different areas or different period of time during the same day or during different maturity stages. This has been reported for Allium sativum [24][25][26] and for Lavandula angustifolia [14,[27][28][29][30] and Melissa officinalis [4,12,13,16,[31][32][33][34][35][36]].…”

Section: Biosynthesis Of Terpenoidssupporting

confidence: 58%

Essential Oil’s Chemical Composition and Pharmacological Properties

Fokou¹,

Dongmo²,

Boyom³

2020

Essential Oils - Oils of Nature

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Essential oil, sent by nature, is a complex mixture of volatile secondary metabolites. Its composition varies along with many parameters that can lead to misunderstanding of its wonderful pharmacological property. In fact, from postharvest treatment to the compound's identification through extraction approaches, the original chemotype of essential oils can be misdescribed. The pharmacological potentials of these oils are well known in the traditional system since time immemorial. Nowadays, some chemotypes of these oils had shown the effect against WHO's top 10 killer diseases. But the misuses of these essential oils are in part due to the lack of robust and easy analysis strategy that can allow the quality of the essential oils.

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Section: Biosynthesis Of Terpenoidssupporting

confidence: 58%

Essential Oil’s Chemical Composition and Pharmacological Properties

Fokou¹,

Dongmo²,

Boyom³

2020

Essential Oils - Oils of Nature

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“…On the basis of the presented observations, it is obvious that L. angustifolia , Lavandula stoechas , and Lavandula dentata contain large amounts of eucalyptol and camphor (Table 1 and Table 2). It should also be noted that lavender oil from Brazil [10] contains borneol at a concentration of 22.4%, which is much higher than that in other L. angustifolia oils (Table 1). Although L. abrialis oil from France [11] and L. bipinnata from Algeria [12] contain large amounts of camphor, they do not contain eucalyptol (Table 2).…”

Section: Introductionmentioning

confidence: 99%

Chemical Composition of Two Different Lavender Essential Oils and Their Effect on Facial Skin Microbiota

et al. 2019

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Lavender oil is one of the most valuable aromatherapy oils, its anti-bacterial and anti-fungal activities can be explained by main components such as linalool, linalyl acetate, lavandulol, geraniol, or eucalyptol. The aim of the study was to assess the anti-microbial effects of two different lavender oils on a mixed microbiota from facial skin. The commercial lavender oil and essential lavender oil from the Crimean Peninsula, whose chemical composition and activity are yet to be published, were used. Both oils were analysed by gas chromatography coupled to mass spectrometry. The composition and properties of studied oils were significantly different. The commercial ETJA lavender oil contained 10% more linalool and linalyl acetate than the Crimean lavender oil. Both oils also had different effects on the mixed facial skin microbiota. The Gram-positive bacilli were more sensitive to ETJA lavender oil, and Gram-negative bacilli were more sensitive to Crimean lavender oil. However, neither of the tested oils inhibited the growth of Gram-positive cocci. The tested lavender oils decreased the cell number of the mixed microbiota from facial skin, but ETJA oil showed higher efficiency, probably because it contains higher concentrations of monoterpenoids and monoterpenes than Crimean lavender oil does.

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“…In this study, DA‐EO displays very promising schistosomicidal activity against Schistosoma mansoni adult worms in vitro , with LC 50 values of 6.50 ± 0.38, 3.66 ± 1.06, and 3.65 ± 0.76 μg/ml at 24, 48, and 72 h, respectively. Moreover, DA‐EO was much more active than other essential oils previously investigated by our research group, which only presented significant activity only at concentrations equal to or higher than 100 μg/ml . Monzote and co‐workers reported that the monoterpene ascaridole accounted for the antileishmanial effect of DA‐EO collected in Cuba, with a LC 50 = 0.1 ± 0.01 μg/ml.…”

Section: Resultsmentioning

confidence: 58%

Chemical Composition, Antibacterial, Schistosomicidal, and Cytotoxic Activities of the Essential Oil of Dysphania ambrosioides (L.) Mosyakin & Clemants (Chenopodiaceae)

Soares

Dias

Vieira

et al. 2017

Chemistry & Biodiversity

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We have investigated the chemical composition and the antibacterial activity of the essential oil of Dysphania ambrosioides (L.) Mosyakin & Clemants (Chenopodiaceae) (DA-EO) against a representative panel of cariogenic bacteria. We have also assessed the in vitro schistosomicidal effects of DA-EO on Schistosoma mansoni and its cytotoxicity to GM07492-A cells in vitro. Gas chromatography (GC) and gas chromatography-mass spectrometry (GC/MS) revealed that the monoterpenes cis-piperitone oxide (35.2%), p-cymene (14.5%), isoascaridole (14.1%), and α-terpinene (11.6%) were identified by as the major constituents of DA-EO. DA-EO displayed weak activity against Streptococcus sobrinus and Enterococcus faecalis (minimum inhibitory concentration (MIC) = 1000 μg/ml). On the other hand, DA-EO at 25 and 12.5 μg/ml presented remarkable schistosomicidal action in vitro and killed 100% of adult worm pairs within 24 and 72 h, respectively. The LC values of DA-EO were 6.50 ± 0.38, 3.66 ± 1.06, and 3.65 ± 0.76 μg/ml at 24, 48, and 72 h, respectively. However, DA-EO at concentrations higher than 312.5 μg/ml significantly reduced the viability of GM07492-A cells (IC = 207.1 ± 4.4 μg/ml). The selectivity index showed that DA-EO was 31.8 times more toxic to the adult S. mansoni worms than GM07492-A cells. Taken together, these results demonstrate the promising schistosomicidal potential of the essential oil of Dysphania ambrosioides.

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Chemical composition, antischistosomal and cytotoxic effects of the essential oil of Lavandula angustifolia grown in Southeastern Brazil

Cited by 30 publications

References 41 publications

Essential Oil’s Chemical Composition and Pharmacological Properties

Essential Oil’s Chemical Composition and Pharmacological Properties

Chemical Composition of Two Different Lavender Essential Oils and Their Effect on Facial Skin Microbiota

Chemical Composition, Antibacterial, Schistosomicidal, and Cytotoxic Activities of the Essential Oil of Dysphania ambrosioides (L.) Mosyakin & Clemants (Chenopodiaceae)

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