2012
DOI: 10.1590/s0102-695x2012005000107
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Phytochemistry and bioactivity of Pedicularis sibthorpii growing in Iran

Abstract: Abstract:The methanol extract of the aerial parts of the medicinal plant Pedicularis sibthorpii Boiss., Scrophulariaceae, growing in the Azerbaijan province of Iran, was found to be active in the 2,2-diphenyl-1-picryl-hydrazyl (DPPH) and the antibacterial agar well diffusion assays, but no general toxicity was observed in the brine shrimp lethality assay. A combination of solid-phase extraction (SPE) and preparative reversed-phase high-performance liquid chromatography (prep-RP-HPLC) analyses of the methanolic… Show more

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Cited by 8 publications
(4 citation statements)
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“…Identification of the metabolites was mainly achieved by means of thin layer chromatography (TLC), infrared (IR), ultraviolet (UV), optical rotation (OR), nuclear magnetic resonance (NMR), and mass spectrometry (MS) techniques. Finally, preliminary analysis of the metabolite contents was performed via the Folin–Cocalteau test for the total phenolic content (TPC), the aluminium chloride colorimetric assay for the total flavonoid content (TFC), Dragendorff’s reagent test for the presence of alkaloids, and the ferric chloride test for the presence of tannins [15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56,57,58,59,60,61,62,63,64,65,66,67,68,69,70,71,72,73,74,75,76,77,<...>…”
Section: Methodologies For the Phytochemical Analysismentioning
confidence: 99%
“…Identification of the metabolites was mainly achieved by means of thin layer chromatography (TLC), infrared (IR), ultraviolet (UV), optical rotation (OR), nuclear magnetic resonance (NMR), and mass spectrometry (MS) techniques. Finally, preliminary analysis of the metabolite contents was performed via the Folin–Cocalteau test for the total phenolic content (TPC), the aluminium chloride colorimetric assay for the total flavonoid content (TFC), Dragendorff’s reagent test for the presence of alkaloids, and the ferric chloride test for the presence of tannins [15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56,57,58,59,60,61,62,63,64,65,66,67,68,69,70,71,72,73,74,75,76,77,<...>…”
Section: Methodologies For the Phytochemical Analysismentioning
confidence: 99%
“…Plant-derived compounds with antibacterial and antifungal activities have been identified and reviewed (Ahmad & Beg, 2001;Aqil & Ahmad, 2007;Gangoué-Piéboji et al, 2009;Giordani et al, 2002;Khodaie et al, 2012;Rabe & van Staden, 1997). However, the antibacterial and antifungal role of Trigonella is recently being uncovered.…”
Section: Antibacterial and Antifungal Effect Of Trigonellamentioning
confidence: 99%
“…It is aphrodisiac by increasing sperm percent, viability, motility and serum total testosterones (61-63). Ginger is a sialagogue (57), increases and stimulates peripheral circulation (59), it is also useful to gingivitis (60), depression in cardiovascular system (10, 34, 36, 54), dementia (66-68) and prevention of constipation (10, 61). …”
Section: Evidence Aquisitionmentioning
confidence: 99%