Efeitos antidiabéticos de plantas medicinais

Abstract

RESUMO:Diabetes mellitus (DM) é uma doença metabólica crônica caracterizada por hipeglicemia que tem impacto significante em seus pacientes. Sua incidência está crescendo rapidamente conduzindo para aumento no custo dos cuidados da doença e de suas complicações. O tratamento envolve, além de controle dietético e atividade física, o uso de fármacos que ocasionam efeitos colaterais para atingir ações farmacológicas desejadas. Entretanto, produtos de plantas são, freqüentemente, considerados menos tóxicos e com menos efeitos colaterais que drogas sintéticas e amplamente utilizadas pela população. Nesse trabalho várias espécies de plantas utilizadas experimentalmente ou na medicina popular, agindo de diferentes formas de modo a controlar glicemia e/ou inibir sintomas e complicações características da diabetes serão revisadas para avaliação de seus supostos efeitos terapêuticos.Unitermos: Diabetes, glicose, hipoglicemia, colesterol, estresse oxidativo.ABSTRACT: "Antidiabetic effects of the medicinal plants". Diabetes mellitus (DM) is a chronic metabolic disease characterized by hyperglycemy that has a significant impact for their patients. Its incidence is raising leading to an increase in the cost of the cares of the disease and of its complications. The treatment involves, besides dietary control and physical activity, the use of drugs that cause side effects to reach wanted pharmacological actions. However, products of plants are, frequently, considered less poisonous and with fewer side effects than synthetic drugs and widely used by the population. In this paper, several species of plants, used experimentally or in the popular medicine, acting by different ways to control glycemia and/or to inhibit symptoms and characteristic complications of the diabetes, they will be reviewed for evaluation of their supposed therapeutic effects.

Evaluation of the Hypoglycemic Properties ofAnacardium humileAqueous Extract

“…Dornas et al [31] reported that nephrotoxicity induced by gentamicin can be attenuated by gallic acid, one of the major components among the phenolic compounds present in the extract of A. humile . According to these authors, the phenolic compounds participate in increasing the antioxidant function, and due to their action as metal chelators and enzyme modulators, they may attenuate renal damage caused by oxidative changes.…”

Improvement of bone repair in diabetic rats subjected to ƛ780 nm low-level laser therapy

“…The hyperglycemic effects of alloxan is a result of irreversible damage in β cells of the islets of Langerhans of pancreas with consequent primary insulin deficiency. This biochemical mechanism triggers a three-phase response in glucose levels during the first hours of administration, followed by the establishment of permanent diabetes in 24 subsequent hours 17 .…”

Flavone complexes of Ti and Zr active in ethylene polymerization

“…The basic structure of these compounds consists of 15 carbon atoms arranged into three rings (C6-C3-C6), two substituted phenolic rings (A and B) and a pyrone ring (C) coupled to ring A. The carbon atoms are numbered 2-10 in A and C rings and 1 to 6 in B ring [10]. There are several classes of flavonoids differing in the oxidation state and position of hydroxyl and methoxy groups in the two phenyl rings.…”