Atividade analgésica do extrato da Pectis jangadensis (S. Moore)

Abstract

RESUMO:A planta Pectis jangadensis, popularmente conhecida como "roxinha", "erva do carregador" ou "coentro da chapada" é utilizada em chás pela população matogrossense, como calmante. Não há estudo na literatura sobre qualquer atividade farmacológica dessa planta. Nosso objetivo foi avaliar atividade analgésica de seu extrato hidro-alcoólico nas doses de 100, 500 e 1000 mg/kg pelos métodos de Contorções induzidas pelo ácido acético e teste da formalina. Os nossos resultados demonstram que não houve diferença significativa entre o grupo controle e os grupos tratados com diferentes doses do extrato tanto em relação ao número de contorções induzidas pelo ácido acético quanto ao tempo de lambedura da pata, na fase 1 e 2, induzida pela formalina. Portanto, pelo menos, por via oral, parece que o extrato hidro-alcoólico da Pectis jangadensis não apresenta atividade analgésica. Unitermos:Pectis jangadensis, Asteraceae, atividade analgésica, "roxinha". ABSTRACT: "Preliminary evaluation of Pectis jangadensis (S. Moore) analgesic activity's".The plant Pectis jangadensis, popularly known as "roxinha", "erva do carregador" or "coentro da chapada" is used in teas by the matogrossense's people, as a calmative. There isn't any study in the literature about its pharmacologic activity. Our object was to evaluate its extract hidroalcoolic analgesic activity in doses of 100, 500 and 1000 mg/kg by the methods of abdominal writhing induced by acetic acid and the Formalin test. The results show that there wasn't significant difference between the control groups and the groups treated with different doses of the extract in both testes. Therefore, at least by oral, seems that the Pectis jangadensis' hidroalcoolic extract doesn't have analgesic activity.

Traditional use, chemical composition and antimicrobial activity of Pectis brevipedunculata essential oil: A correlated lemongrass species in Brazil

“…Also in southeast region some Pectis species have traditional indication use as infusions or juice drink preparations for hypertension, stomach disorders and colds (Agra et al, 2007). Calmative and analgesic properties were also reported for some Pectis tea preparations (Soares et al, 2009;Oliveira et al, 2011). The leaves of these species are used as edible parts specially as condiment raw or cooked, being also used as flavouring due to the strong lemon scent.…”

Brazilian scientific production on herbal medicines used in dentistry

“…Besides the antifungal and antibacterial potential of medicinal plants against dental infections, it is important to study and evaluate other properties such as anesthetic, analgesic (Soares et al, 2009), antiviral (Kazyiama et al, 2012, antimutagenic and antitumor (Maciel et al, 2002) activities. Toxicological studies addressing possible adverse effects of medicinal plants (Cowan, 1999;Veiga Júnior et al, 2005) are also scarce, given their importance for the evolution and progression of researches in this field.…”

Pharmacological activity ofCostus spicatusin experimentalBothrops atroxenvenomation

“…The method used was based on the protocol previously described by Hunskaar and Hole (1987) with modifications recommended by Soares et al (2009) and De Sousa et al (2012). As a further modification, formalin used for pain induction was substituted by BAV at 0.20 mg/kg.…”