Constituintes químicos das folhas e do caule de Coccoloba mollisCasaretto (Polygonaceae)

Abstract

RESUMO:O estudo químico das frações neutra em hexano das folhas e em diclorometano do caule de Coccoloba mollis resultou no isolamento de um triterpeno pentacíclico (simiarenol), que pela primeira vez ocorre em Polygonaceae, dois fi toesteróides (sitostenona e sitosterol), um diterpeno (trans-fi tol) e de um benzenóide (ácido vanílico) que está sendo descrito pela vez neste gênero. A identifi cação estrutural destes compostos foi feita com base na análise dos dados espectrais (IV, EM e RMN, incluindo DEPT e HMQC), bem como pela comparação com dados descritos na literatura.Unitermos: Coccoloba mollis, Polygonaceae, triterpeno, benzenóide, fi toesteróides, diterpeno.ABSTRACT: "Chemical constituents from leaves and stem of Coccoloba mollis Casaretto (Polygonaceae)". This work describes the isolation of a pentacyclic triterpene (simiarenol), described for the fi rst time in this family, two phytosteroids (sitostenone and sitosterol), a diterpene (trans-phytol) and a benzenoid (vanillic acid), described for the fi rst time in this genus, from leaves and stem of Coccoloba mollis. These compounds were identifi ed on basis of their spectral data (IR, MS and NMR, including DEPT and HMQC), as well as by comparison with literature data.

Phytochemical and antifungal activity of anthraquinones and root and leaf extracts of Coccoloba mollis on phytopathogens

“…(Li et al, 1999) In the present work, the extracts of C. mollis leave and roots showed antifungal activities against important fungal phytopathogens. The antifungal activity of C. mollis could be due to the presence of long chain hydrocarbons, carboxyl esters and taraxerone and of other metabolites isolated from the ethanol extract of the leaves and stems of C. mollis Casar, such as simiarenol (pentacyclic triterpene), one diterpene and two phytosteroids (Oliveira et al, 2008). The results suggested that the antifungal activity correlated with the presence of triterpenes, such as taraxerone.…”

Larvicidal activity of 94 extracts from ten plant species of northeastern of Brazil against Aedes aegypti L. (Diptera: Culicidae)

“…From leaves, stem barks and stems of G. grazielae, beside a phytosteroid (sitostenone), were isolated six triterpenes (α-amyrin acetate, cycloartenone, 3β,19α,23-trihydroxyurs-12-ene, and ursolic, 3-β-O-β-Dglucopyranosylquinovic, 3β,6β,19α,23-tetrahydroxyurs-12-en-28-oic acids;Lima et al 2009). On the other hand, from leaves and stems of C. mollis a pentacyclic triterpene (simiarenol), a diterpene (trans-phytol), a benzenoid (vanillic acid), and two phytosteroids (sitostenone and sitosterol) were isolated (Oliveira et al 2008a) while from fruits and stems of T. americana, five derivative phenolic compounds (moupinamide, gallic acid, quercetin 3-O-α-L-arabinofuranoside, quercetin, and vanicoside D) were obtained (Oliveira et al 2008b). Subsequently, evaluation of these compounds will be needed to identify the active component of these species.…”

Coccoloba alnifoliaLeaf Extract as a Potential Antioxidant Molecule Using In Vitro and In Vivo Assays

“…Ashmawy et al [ 12 ] working with C. uvifera leaves detected ellagic acid, benzoic acid, o -coumaric acid, rutin, myricetin, and quercetin in water, acetone, and ethanol extracts. Furthermore, for C. mollis triterpenes, diterpenes, anthraquinones, phytosteroids, and benzenes were identified in leaves and shoots [ 11 ].…”