Influence of an aqueous extract of Hypericum perforatum (Hypericin) on the survival of Escherichia coli AB1157 and on the electrophoretic mobility of pBSK plasmid DNA

Santos-Filho, Sebastião David; Bernardo, Raquel Mattos; Santos, Kelly Cristina Moreira dos; Fonseca, A S; Bernardo-Filho, Mário

doi:10.1590/s0102-695x2008000300003

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2017

2023

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“…Hypericins and hyperforin were both considered to be responsible for the antidepressant effect of Hypericum perforatum (4). Also, hypericin has a protective effect on the plasmid DNA and E. coli against the reduction of SnCl 2 (5).…”

Section: Introductionmentioning

confidence: 99%

A Simple Method for Extraction and Purification of Hypericins from St John’s Wort

Ramezani

Zamani

2017

Jundishapur J Nat Pharm Prod

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Hypericin was extracted from Hypericum perforatum L. using a different extraction procedure. Highest amounts of hypericins were extracted by ultrasonic methods using methanol: acetone 2:1 as an extracting solvent. Hypericin contents of the extract was purified by passing it through 2 series of 70 × 5 mm glass columns, each filled with 800 mg of 35 -70 mesh silica gel, followed by elution with MeOH: acetone: CH2Cl2 (75:10:15). The extent of purification was determined by HPLC. The amount of purified hypericins, which was extracted from Hypericum perforatum, was 5.105 mg per gram dried plant leaves.

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Section: Introductionmentioning

confidence: 99%