Nueva fuente de quinoles, la superficie foliar de Pentacalia ledifolia y Pentacalia corymbosa y sus propiedades antifúngicas

Abstract

RESUMO: "Nova fonte de quinóides, a superfi cie foliar de Pentacalia ledifl ora e Pentacalia corymbosa e suas propriedades antifúngicas". Foi demonstrada a ação antifúngica do extrato clorofórmico e de duas substâncias isoladas da superfície foliar de Pentacalia ledifolia (H.B.K.) Cuatr. e P. corymbosa (Benth) Cuatr. frente aos fungos fi topatógenos Fusarium oxysporum e Botrytis cinerea, cultivados em BDA (batata-dextrose-ágar). Destes extratos foram isolados, além de cumarinas já identifi cadas em estudos anteriores, dois derivados quinóides: (1-hidroxi-4-oxo-2,5-ciclohexadienil) acetato de metila ou jacaranona e (1-hidroxi-4-oxo-2,5-ciclohexadienil) acetato de etila ou metiljacaranona. Para o (1-hidroxi-4-oxo-2,5-ciclohexadienil) acetato de etila foi calculado CI 50 de 650 μg/mL para os dois tipos de fungos e o (1-hidroxi-4-oxo-2,5-ciclohexadienil) acetato de metila teve um CI 50 de 660 μg/mL. Unitermos:Pentacalia ledifolia, Pentacalia corymbosa, Asteraceae, Senecioneae, atividade antifúngica, quinóides.ABSTRACT: "New source of quinols, the surface of Pentacalia ledifolia and Pentacalia corymbosa leaves and its antifungal activity". Quinols identifi ed in the surface waxes of Pentacalia ledifolia (H.B.K.) Cuatr and P. corymbosa (Benth) Cuatr. leaves, possess antifungal activity against Fusarium oxysporum and Botrytis cinerea, cultured on PDA (potato-dextrose-agar) medium. These extracts were prepared by dipping fresh leaves in chloroform for 5 min, and afforded ethyl-(1-hydroxy-4-oxocyclohexa-2,5-dien-1-yl) acetate and methyl-(1-hydroxy-4-oxocyclohexa-2,5-dien-1-yl) acetate, the major surface compounds.

Anti-malarial, anti-trypanosomal, and anti-leishmanial activities of jacaranone isolated from Pentacalia desiderabilis (Vell.) Cuatrec. (Asteraceae)

“…Comparison of spectroscopic data with those reported in the literature (Lajide et al 1996) allowed the identification of bioactive compound as methyl (1-hydroxy-4-oxo-2,5-cyclohexandienyl) acetate, known as jacaranone (Fig. 2) and previously isolated from P. corymbosa and P. ledifolia (Pedrozo et al 2006). …”

“…The chemical composition of Pentacalia reports the isolation of terpenoids and phenylpropanoids from Pentacalia ephiphytica, Pentacalia andicola, Pentacalia firmipes, and Pentacalia archieri (Bohlmann and Ziesche 1979;Bohlmann et al 1984) while steroids, triterpenes, coumarins, and flavonoids were obtained from Pentacalia corymbosa (Torrenegra et al 2000). Recently, two quinoids were isolated from P. ledifolia and P. corymbosa, which showed antifungal activity (Pedrozo et al 2006). In Brazil, only two species have been described: P. desiderabilis, whose occurrence is restricted to the south, southeast, and northeastern regions, and P. tropicalis, found only in the EspÌrito Santo and Rio de Janeiro states.…”

Variabilidad química de extractos y fracciones obtenidas de tres especies de la tribu Senecioneae: Gynoxys hirsuta, Pentacalia ledifolia, Senecio pampae

“…Caricaceae, Salicaceae, Scrophularicaceae, Bignoniaceae entre otras, el (1hidroxi-4-oxo-2,5-ciclohendienil) acetato de metilo llamado también jacaranona fue aislado de Jacaranda caucana y de Senecio cannabifolius, en esta última especie también se identificó el (1-hidroxi-4-oxo-2,5-ciclohexandienil) acetato de etilo o metiljacaranona reportándoseles una acción inhibitoria del crecimiento de la larva Spodoptera litura, un díptero que ataca plantas de tabaco (Pedrozo,J et al 2006).…”