The isolation of fragnettin, the so called 'flavonoid crystals', from three species of Prosthechea, namely P. fragrans, P. vespa and P. caetensis, and its characterization as 8-C-β-D-quinovopyranosyl apigenin is described. The possibility of fragnettin (8-C-β-D-quinovopyranosyl apigenin), the 'flavonoid crystals' absent in the genus Encyclia, being the marker of the genus Prosthechea is suggested.