Estudo farmacognóstico de galhos de Vanillosmopsis erythropappa Schult. Bip. - Asteraceae

Souza, O.V.S.; Oliveira, M. Silva de; Rabello, Sabrina; Cunha, R.O.; Costa, Bernard; Leite, Magda Narciso

doi:10.1590/s0102-695x2003000300019

Cited by 16 publications

(13 citation statements)

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“…Eremanthus erythropappus (DC) McLeisch (Asteraceae) (Vanillosmopsis erythropappa Schultz-Bip), known commonly as candeia, is used in folk medicine as an antiphlogistic and antimicrobial agent (Sousa et al 2003). The essential oil obtained from the wood of E. erythropappus contains a-bisabolol, costunolide and eremanthine (Lopes et al 1991;Braun et al 2003), compounds with the cyclocostunolide and eremanthine skeleton (Lima et al 1985;Lopes et al 1991), vanillosmin (Corbrella et al 1974), 15-deoxygoyazenzolide (Vichnewski et al 1976) and lychnopholide (Vichnewski et al 1989).…”

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confidence: 99%

“…The essential oil obtained from the wood of E. erythropappus contains a-bisabolol, costunolide and eremanthine (Lopes et al 1991;Braun et al 2003), compounds with the cyclocostunolide and eremanthine skeleton (Lima et al 1985;Lopes et al 1991), vanillosmin (Corbrella et al 1974), 15-deoxygoyazenzolide (Vichnewski et al 1976) and lychnopholide (Vichnewski et al 1989). The a-bisabolol, present in other members of Asteraceae such as Chamomilla recutita, exhibits anti-inflammatory properties (Jakovlev et al 1979) and has been widely used in pharmaceutical and cosmetic products (Sousa et al 2003).…”

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confidence: 99%

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Antinociceptive and anti-inflammatory effects of the essential oil from Eremanthus erythropappus leaves

Sousa

Silvério

Del-Vechio-Vieira

et al. 2008

Journal of Pharmacy and Pharmacology

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The chemical composition of the essential oil from air-dried leaves of Eremanthus erythropappus was studied. The main compounds were beta-pinene (23.24%), beta-caryophyllene (22.92%), beta-myrcene (10.03%) and germacrene D (9.40%). The essential oil had an LD50 of 2.90 g kg(-1) in mice. Doses of 200 and 400 mg kg(-1) inhibited 10.69% and 27.06% of acetic-acid-induced writhing in mice, respectively. In the formalin-induced nociception test in mice, the essential oil inhibited the first phase of paw licking by 29.13% (400 mg kg(-1)) and the second phase by 32.74% (200 mg kg(-1)) and 37.55% (400 mg kg(-1)). In the hot-plate test in mice, doses of 200 mg kg(-1) and 400 mg kg(-1) significantly increased the reaction time after 30, 60 and 90 min of treatment. Doses of 200 and 400 mg kg(-1) inhibited carrageenan-induced paw oedema in rats by 15.18% and 36.61%, respectively. Doses of 200 and 400 mg kg(-1) administered 4 h before intrapleural injection of carrageenan significantly reduced exudate volume (by 20.20% and 48.70%, respectively) and leucocyte mobilization (by 5.88% and 17.29%, respectively). These results demonstrate that E. erythropappus has analgesic and anti-inflammatory properties, supporting the use of this plant in folk medicine.

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confidence: 99%

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confidence: 99%

Antinociceptive and anti-inflammatory effects of the essential oil from Eremanthus erythropappus leaves

Sousa

Silvério

Del-Vechio-Vieira

et al. 2008

Journal of Pharmacy and Pharmacology

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“…A preliminary phytochemical screening was carried out on an extract obtained by percolation of the dried and powdered fruit with 70% ethanol. The following chemical reactions were used to characterize secondary metabolites: 12 Shinoda and aluminum chloride reactions for flavonoids; gelatin, iron, and copper salts for tannins; Dragendorff, Bouchardat, Mayer, and Bertrand precipitation reactions for alkaloids; Borntraeger reaction for anthraquinones; Kedde and Liberman-Buchard for steroids; and foaming index for saponins.…”

Section: Methodsmentioning

confidence: 99%

Natural Products fromGarcinia brasiliensisasLeishmaniaProtease Inhibitors

Pereira

Assis

Juliano

et al. 2011

Journal of Medicinal Food

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The growing list of drug-resistant microorganisms and the persistence of deaths due to diarrhea are compelling reasons to study plants in search of new therapeutic agents. The chemical constitution and popular use of the edible fruits of Campomanesia xanthocarpa O. Berg motivated this study to assess the antimicrobial and antidiarrheal properties of the fruits. An extract in 70% ethanol was prepared, and its antimicrobial activity was tested against several strains of bacteria by the agar diffusion and microdilution methods. Antidiarrheal activity was analyzed by testing intestinal motility in an animal model. Preliminary phytochemical study indicated the presence of flavonoids, saponins, and tannins in the hydroalcoholic extract. Antimicrobial activity was significant, but the minimum inhibitory concentration proved to be higher than the maximum extract concentration tested. The extract did not show significant activity for intestinal motility. Although this fruit extract did not show great results as an antimicrobial or antidiarrheal agent, the study contributes to the search for new plant agents and could be referred to as a research protocol by investigators in this area.

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“…MacLeisch, sinonimizada de Vanillosmopsis erythropappa SchultzBip, pertencente à família Asteraceae e conhecida popularmente como "candeia-da-serra" (Sousa et al, 2003), é encontrada na Argentina, norte e leste do Paraguai e no Brasil (Carvalho, 1994). No Brasil predomina nos Estados das regiões Sudeste, Sul e Centro-Oeste (Carvalho, 1994;Pedralli et al, 1997).…”

Section: Introductionunclassified

Caracterização morfoanatômica das folhas de Eremanthus erythropappus (DC.) MacLeisch, Asteraceae

Dutra¹,

Ferraz²,

Pimenta³

et al. 2010

Rev. bras. farmacogn.

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RESUMO:Eremanthus erythropappus (DC.) MacLeisch (Asteraceae), popularmente conhecida como "candeia-da-serra", é uma espécie utilizada na medicina tradicional como cicatrizante e antimicrobiano. O objetivo do presente trabalho foi comparar o número de tricomas glandulares nas folhas jovens e adultas de E. erythropappus, assim como realizar a caracterização morfoanatômica destas folhas. Secções transversais e paradérmicas das folhas foram submetidas às microtécnicas fotônicas e à microscopia eletrônica de varredura. A quantificação dos tricomas glandulares foi realizada em folhas jovens e adultas com auxílio de câmara clara. As folhas são alternas ou fasciculadas e a lâmina foliar possui epiderme uniestratificada, revestida por cutícula delgada e lisa e mesofilo dorsiventral. Em ambas as faces da epiderme, ocorrem estômatos predominantemente anomocíticos e tricomas glandulares inseridos em depressões. Na face abaxial observam-se numerosos tricomas tectores. O parênquima paliçádico é uniestratificado e o parênquima voltado para a face abaxial é formado por três a cinco camadas de células com disposição compacta. As folhas jovens e adultas apresentam respectivamente 21,78±5,83 e 17,80±6,69 tricomas glandulares na face adaxial. A análise morfoanatômica das folhas de E. erythropappus mostra-se um método rápido e prático para a identificação e controle de qualidade de espécies vegetais utilizadas na terapêutica. Unitermos:Eremanthus erythropappus, Asteraceae, morfoanatomia.ABSTRACT: "Leaf morpho-anatomical characterization of Eremanthus erythropappus (DC.) MacLeisch, Asteraceae". Eremanthus erythropappus (DC.) MacLeisch (Asteraceae), commonly known as 'candeia-da-serra', is a plant used in folk medicine as wound healing and antimicrobial. The aim of this study was to compare the number of glandular trichomes between the young and the mature leaves, as well as to perform the morpho-anatomical characterization of E. erythropappus leaves. Transverse and paradermal sections of the leaves were prepared according to light and scanning microtechniques for the morpho-anatomical characterization. The quantification of glandular trichomes on the adaxial surface of the epidermis was evaluated in young and mature leaves with camera lucida. The leaves are alternate or fasciculate and the blade has uniseriate epidermis coated with thin and smooth cuticle and dorsiventral mesophyll. There are predominantly anomocytic stomata on both surfaces, as well as glandular trichomes located in epidermal depressions. Various nonglandular trichomes are encountered on the abaxial surface. The palisade parenchyma consists of a single layer of cells and the parenchyma which is faced to the abaxial surface comprehends three to five layers of cells in compact arrangement. The young and mature leaves showed, respectively, 21.78±5.83 e 17.80±6.69 glandular trichomes on the adaxial side. The morphoanatomical analysis of E. erythropappus leaves has proved to be a practical and rapid method for the identification and quality control of the vegetal species...

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Estudo farmacognóstico de galhos de Vanillosmopsis erythropappa Schult. Bip. - Asteraceae

Cited by 16 publications

References 2 publications

Antinociceptive and anti-inflammatory effects of the essential oil from Eremanthus erythropappus leaves

Antinociceptive and anti-inflammatory effects of the essential oil from Eremanthus erythropappus leaves

Natural Products fromGarcinia brasiliensisasLeishmaniaProtease Inhibitors

Caracterização morfoanatômica das folhas de Eremanthus erythropappus (DC.) MacLeisch, Asteraceae

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