Composição química da própolis: vitaminas e aminoácidos

Moreira, Telma Franco

doi:10.1590/s0102-695x1986000100003

Cited by 15 publications

(8 citation statements)

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“…A high flavonoid total was detected (40.8 mg/g propolis) and some were identified, such as galangin (9%), chrysin (3.8%), and quercetin (2%). Moreira [39] analyzed vitamin and amino acid concentrations in propolis samples commercialized in São Paulo. Histidine is among several amino acids detected and vitamins B1 and B2 but not vitamin C were also detected.…”

Section: Discussionmentioning

confidence: 99%

Inhibitory effect of propolis and bee venom on the mutagenicity of some direct- and indirect-acting mutagens

Varanda

Monti

Tavares

1999

Teratogenesis Carcinog. Mutagen.

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Section: Discussionmentioning

confidence: 99%

Inhibitory effect of propolis and bee venom on the mutagenicity of some direct- and indirect-acting mutagens

Varanda

Monti

Tavares

1999

Teratogenesis Carcinog. Mutagen.

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“…Além disso, a variabilidade genética das abelhas rainhas também infl uencia na composição química (Park et al, 1998). Deste modo, um número signifi cativo de trabalhos com a química da própolis foi publicado para entender que sua composição varia grandemente e depende da fl ora local e da região de coleta (Moreira, 1986;Bankova, 2005a;Sousa et al, 2007).…”

Section: Composição Químicaunclassified

Própolis: atualizações sobre a química e a farmacologia

Lustosa¹,

Galindo²,

Nunes³

et al. 2008

Rev. bras. farmacogn.

103

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RESUMO:Própolis é uma mistura complexa, formada por material resinoso e balsâmico. Sua composição química é complexa e variada, estando relacionada com a fl ora de cada região visitada pelas abelhas e com o período de coleta da resina. Inclui fl avonóides, ácidos aromáticos, terpenóides e fenilpropanóides, ácidos graxos e vários outros compostos. A própolis tem sido objeto de intensos estudos farmacológicos e químicos nos últimos 30 anos. Em várias partes do mundo é indicada para melhorar a saúde e prevenir doenças. Atualmente, é disponível em várias formas farmacêuticas como cápsulas, extratos, enxaguatório bucal, na forma de pó, entre outras. Ainda são necessários estudos correlacionando a composição química com a atividade biológica, defi nindo cada tipo de própolis com a sua aplicação terapêutica. É uma tarefa imprescindível para um mercado cada vez maior e exigente em todo o mundo.Unitermos: Própolis, constituintes químicos, atividade biológica.ABSTRACT: "Propolis: updates on chemistry and pharmacology". Propolis (bee glue) is a complex mixture, formed by resinous and balsamic material. Its chemical composition is variable and complex, being related with the fl ora of each region visited by the bees and with the period of resins collection. Flavonoids, aromatic acids, terpenoids and phenylpropanoids, fatty acids, and other compounds are found in propolis. In the last 30 years, propolis has become subject of intense pharmacological and chemical studies. In different parts of the world it is indicated to improve health and prevent illnesses. Currently, it is available in some pharmaceutical forms as capsules, extracts, mouthrinses, powder form, among others. Indeed, studies correlating the chemical composition with the biological activity are necessary, defi ning each type of propolis with its therapeutic application. It is an essential task for a market ever bigger and demanding in the whole word.

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“…Propolis from temperate zones generally consists of 50-60% resins and balsams, 30-40% of wax, 5-10% of essential and aromatic oils, 5% of pollen, and 5% of other substances (Mendoza et al, 1991). These substances comprise more than 210 different compounds identifi ed so far, such as aliphatic acids, aromatic esters and acids, fl avonoids, fatty acids, carbohydrates, aldehydes, amino acids, ketones, chalcones, dihydrochalcones, terpenoids, vitamins (B1, B2, B6, C, and E), and minerals (aluminum, antimonium, calcium, cesium, copper, iron, lithium, manganese, mercury, nickel, silver, vanadium, and zinc) (Ghisalbert, 1979;Moreira, 1990;Marcucci, 1995;Sousa et al, 2007;Chang et al, 2008;Lustosa et al, 2008). Therefore variation in propolis components could affect its properties (Nakamura et al, 2010).…”

Section: Introductionmentioning

confidence: 99%

Mechanisms of action underlying the anti-inflammatory and immunomodulatory effects of propolis: a brief review

Araújo

Libério

Guerra

et al. 2012

Rev. bras. farmacogn.

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Many biological properties have been attributed to various types of propolis, including anti-inflammatory, antimicrobial, antioxidant, antitumor, wound healing, and immunomodulatory activities. This article reviewed studies published that investigated the anti-inflammatory activity of propolis of different origins and/ or its isolated components, focusing on the mechanisms of action underlying this activity and also addressing some aspects of immunomodulatory effects. The search was performed of the following databases: PubMed, Science Direct, HighWire Press, Scielo, Google Academics, Research Gate and ISI Web of Knowledgement. The anti-inflammatory activity was associated with propolis or compounds such as polyphenols (flavonoids, phenolic acids and their esters), terpenoids, steroids and amino acids. CAPE is the most studied compounds. The main mechanisms underlying the anti-inflammatory activity of propolis included the inhibition of cyclooxygenase and consequent inhibition of prostaglandin biosynthesis, free radical scavenging, inhibition of nitric oxide synthesis, reduction in the concentration of inflammatory cytokines and immunosuppressive activity. Propolis was found to exert an antiinflammatory activity in vivo and in vitro models of acute and chronic inflammation and others studies, indicating its promising potential as anti-inflammatory agent of natural origin and as a source of chemical compounds for the development of new drugs.

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Composição química da própolis: vitaminas e aminoácidos

Cited by 15 publications

References 0 publications

Inhibitory effect of propolis and bee venom on the mutagenicity of some direct- and indirect-acting mutagens

Inhibitory effect of propolis and bee venom on the mutagenicity of some direct- and indirect-acting mutagens

Própolis: atualizações sobre a química e a farmacologia

Mechanisms of action underlying the anti-inflammatory and immunomodulatory effects of propolis: a brief review

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