Tratamento adjuvante nos GISTs

Lourenço, Laércio Gomes; Caponero, Ricardo

doi:10.1590/s0102-67202011000300012

Cited by 2 publications

(1 citation statement)

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“…Neoadjuvant chemotherapy sometimes is indicated in the management of large lesions. Adjuvance is reserved for recurrence or unresectable metastasis 16 , 24 .…”

Section: Introductionmentioning

confidence: 99%

Laparoscopic Resection of Gastrointestinal Stromal Tumors (Gist)

Loureiro

Almeida

Claus

et al. 2016

ABCD, arq. bras. cir. dig.

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Background Gastrointestinal mesenchymal or stromal tumors (GIST) are lesions originated on digestive tract walls, which are treated by surgical resection. Several laparoscopic techniques, from gastrectomies to segmental resections, have been used successfully. Aim Describe a single center experience on laparoscopic GIST resection. Method Charts of 15 operated patients were retrospectively reviewed. Thirteen had gastric lesions, of which ten were sub epithelial, ranging from 2-8 cm; and three were pure exofitic growing lesions. The remaining two patients had small bowel lesions. Surgical laparoscopic treatment consisted of two distal gastrectomies, 11 wedge gastric resections and two segmental enterectomies. Mechanical suture was used in the majority of patients except on six, which underwent resection and closure using manual absorbable sutures. There were no conversions to open technique. Results Mean operative time was 1h 29 min±92 (40-420 min). Average lenght of hospital stay was three days (2-6 days). There were no leaks, postoperative bleeding or need for reintervention. Mean postoperative follow-up was 38±17 months (6-60 months). Three patients underwent adjuvant Imatinib treatment, one for recurrence five months postoperatively and two for tumors with moderate risk for recurrence . Conclusion Laparoscopic GIST resection, not only for small lesions but also for tumors above 5 cm, is safe and acceptable technique.

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“…Neoadjuvant chemotherapy sometimes is indicated in the management of large lesions. Adjuvance is reserved for recurrence or unresectable metastasis 16 , 24 .…”

Section: Introductionmentioning

confidence: 99%