Osteossarcoma: experiência do Serviço de Oncologia Pediátrica da Santa Casa de Misericórdia de São Paulo

Castro, Helaine Cristina de; Ribeiro, Karina de Cássia Braga; Bruniera, Paula

doi:10.1590/s0102-36162008000300002

Cited by 12 publications

(18 citation statements)

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“…One of the main studies is that of Castro et al 15 , which gives an account of the experience of the pediatric oncology service of Santa Casa de Misericórdia de São Paulo with osteosarcoma. The objective of this study was to describe the clinical laboratorial characteristics of 60 cases of children and adolescents with osteosarcoma, determining the rates of event-free survival and of global survival.…”

Section: Discussionmentioning

confidence: 99%

Acompanhamento do paciente tratado de osteossarcoma

Martins

Perez

2012

Acta ortop. bras.

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ObjectiveTo evaluate the value of post-treatment follow-up in osteosarcoma patients.MethodsData were collected through a clinical record, with socio-demographic and clinical data, and information relating to the medical appointment. Descriptive analysis of the data was carried out. The Chi-squared test was used to associate the independent variables with attendance at scheduled follow-up appointments.ResultsWe found a recurrence in 59.6% of cases, of which 58% were lung related; 44% presented clinical complaints and arrived on the scheduled date of the appointment. There was no statistically significant association between the demographic characteristics and early attendance of follow-up visits. 81.3% of the cases who came for the appointment earlier than originally scheduled presented complaints compared to those who did not (p=0.005). Of the cases who presented recurrence, 12.9% attended an appointment late and those who did not present recurrence, 47.6% were late for the appointment (p=0.006).ConclusionIt is seen that the patients who came for an earlier appointment presented more complaints and were associated with the positive result of the exams carried out. The patients who had recurrence and came for an earlier appointment did not present a statistically significant difference in recurrence-free survival. It was observed that distance was not a predominant factor in late attendance at appointments. Level of Evidence II, Retrospective Study.

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Section: Discussionmentioning

confidence: 99%

Acompanhamento do paciente tratado de osteossarcoma

Martins

Perez

2012

Acta ortop. bras.

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“…It accounts for 20% of the primary cancers and 5% of childhood tumors. 8,9 The most common location is in the metaphysis of the long bones that are in the growth phase (such as the distal femur and proximal tibia) and their length varies from person to person. Prevalence is greater among the male gender, with a ratio of 1.5 to 2.1 : 1, occurring generally between the second and third decades of life.…”

Section: Introductionmentioning

confidence: 99%

“…Prevalence is greater among the male gender, with a ratio of 1.5 to 2.1 : 1, occurring generally between the second and third decades of life. [8][9][10] The main signs and symptoms are pain and a progressively increasing local volume, change in sensitivity, redness, the possibility of limited movement, edema, infiltration of the soft tissues, signs of inflammation, and collateral circulation. Pathological fractures can be observed in 15% of cases.…”

Section: Introductionmentioning

confidence: 99%

“…Pathological fractures can be observed in 15% of cases. [9][10][11] The diagnosis is done by clinical history and supplementary exams such as bone scintigraphy with radioisotopes, Computerized Tomography (CAT), and Magnetic Resonance Imaging (MRI), in addition to biopsies from lesioned-tissue samples. The previous study of the type of cancer via biopsy has allowed for a more precise diagnosis with fewer complications after oncological surgeries.…”

Section: Introductionmentioning

confidence: 99%

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Clinical and epidemiological characteristics of adolescent patients with osteosarcoma

Castro¹,

Silva²,

Barroso³

et al. 2014

Acta Fisiátrica

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Osteosarcoma (OS) is a malignant neoplasia that affects the bone tissue with no known cause. It most commonly affects the appendicular skeleton, mainly the femur and tibia bones, in children and adolescents. The surgery treatment consists of a resection of the tumor or amputation of the affected limb, associated with chemotherapy. The earlier it is diagnosed and treated, and the smaller it is, the better the prognosis will be. Objective: The main objective of this study was to present the clinical characteristics and epidemiology of adolescent patients from the Ceará Cancer Hospital (HCC) in the city of Fortaleza. Clinical and epidemiologic data about these patients, who ranged from the age of 10 to 19 years old, was investigated in order to fulfill our objectives with this study. Method: A retrospective cohort study was developed gathering information from patients' charts from the above-mentioned hospital from the period of January 2006 to December 2007. The data was collected through a semi-structured form that consisted of questions that appraised both the clinical and epidemiological characteristics of the patients, as well as the demographic data. After selecting 29 cases, only 26 were used for the analysis due to either incomplete information, abandonment of treatment, or hospital transference. Results: Our results show that Osteosarcoma was found to be more frequent in male patients (57.7%), in patients between 10 and 15 years old (73.1%), in afro-descendant patients (50%), and in patients that came from more rural areas (73.1%). This study also shows that 30.8% of the patients presented a family history of cancer. The symptom that these patients seemed to have in common was pain (24 patients), followed by an increase of local volume (20 patients), and previous trauma (8 patients). The femur bone was affected in 65.4% of the cases, with occurrence of metastasis (76.9%), almost always during the diagnosis and with the majority (15 patients) to the lungs. The treatment consisted of chemotherapy (96.2%) associated with the surgical resection (69.2%) and amputation (73.1%) or limb replacement. Other treatments such as Physical Therapy were prescribed in 42.3% of the cases, mostly during post-surgery (23.1%), and generally just to treat the complications. Conclusion: This study suggests that the common profile of a patient with Osteosarcoma is male, afro-descendant, coming from the more rural areas and presenting a family history of cancer. In conclusion, this study suggests the importance of knowledge about both clinical and epidemiological characteristics of Osteosarcoma patients, so that there is more regard from health professionals concerning multidisciplinary teamwork at the time of the diagnosis.

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“…There are various national studies related to osteosarcoma (treatment, recurrence, results of the Brazilian Cooperative Group), but not exclusively geared towards the follow-up of osteosarcoma, from the point of view of a single institution, as in the present study. One of the main studies is that of Castro et al 15 , which gives an account of the experience of the pediatric oncology service of Santa Casa de Misericórdia de São Paulo with osteosarcoma. The objective of this study was to describe the clinical laboratorial characteristics of 60 cases of children and adolescents with osteosarcoma, determining the rates of event-free survival and of global survival.…”

Section: Discussionmentioning

confidence: 99%

Acompanhamento do paciente tratado de osteossarcoma

Martins¹

View full text Add to dashboard Cite

Objective: To evaluate the value of post-treatment follow-up in osteosarcoma patients. Methods: Data were collected through a clinical record, with socio-demographic and clinical data, and information relating to the medical appointment. Descriptive analysis of the data was carried out. The Chi-squared test was used to associate the independent variables with attendance at scheduled follow-up appointments. Results: We found a recurrence in 59.6% of cases, of which 58% were lung related; 44% presented clinical complaints and arrived on the scheduled date of the appointment. There was no statistically significant association between the demographic characteristics and early attendance of follow-up visits. 81.3% of the cases who came for the appointment earlier than originally scheduled presented complaints compared to those who did not (p=0.005). Of the cases who presented recurrence, 12.9% attended an appointment late and those who did not present recurrence, 47.6% were late for the appointment (p=0.006). Conclusion: It is seen that the patients who came for an earlier appointment presented more complaints and were associated with the positive result of the exams carried out. The patients who had recurrence and came for an earlier appointment did not present a statistically significant difference in recurrence-free survival. It was observed that distance was not a predominant factor in late attendance at appointments. Level of Evidence II, Retrospective Study.

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Osteossarcoma: experiência do Serviço de Oncologia Pediátrica da Santa Casa de Misericórdia de São Paulo

Cited by 12 publications

References 13 publications

Acompanhamento do paciente tratado de osteossarcoma

Acompanhamento do paciente tratado de osteossarcoma

Clinical and epidemiological characteristics of adolescent patients with osteosarcoma

Acompanhamento do paciente tratado de osteossarcoma

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