Resultado do tratamento da tuberculose com estreptomicina, isoniazida e etambutol (esquema SHM)

Picon, Pedro Dornelles; Giustina, Maria de Lourdes Della; Rizzon, Carlos Fernando Carvalho; Bassanesi, Sérgio Luiz; Zanardo, Ana Paula; Michalczuk, Matheus Truccolo; Ricardi, L. R.

doi:10.1590/s0102-35862002000400003

Cited by 4 publications

(6 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Small discrete foci adjacent to the main lesion were seen in most of the patients (Figure 1). outpatients was 2.1%, which is lower than the 7.8% reported by Picon et al (24) However, those authors evaluated only patients, their sample was smaller (n = 231), and the proportion of HIV-infected patients was higher in their study.…”

Section: Resultscontrasting

confidence: 61%

“…(24,25) We found that the prevalence of tuberculous pneumonia among consecutive tuberculosis T cells within the large area of inflammation, as described in cases of pleural effusions in patients with tuberculosis. (16) Leukocytosis with a left shift was observed in only 35.6% of our patients with tuberculous pneumonia, as has been previously reported, (23,24) which is obviously different from what occurs in typical cases of bacterial pneumonia. The good response to treatment with the antituberculosis drugs used, as well as the low frequency of side effects, was as expected for the management of tuberculosis in general.…”

Section: Discussionmentioning

confidence: 90%

“…In two case series involving a total of 93 patients, M. tuberculosis was most often identified by sputum smear microscopy, especially when multiple examinations were conducted. (24,25) The non-classical forms of pulmonary tuberculosis, including pneumonia, are often seen in HIV-infected individuals. In a recent case series of 231 patients with pulmonary tuberculosis, 113 were HIV-infected.…”

mentioning

confidence: 99%

See 2 more Smart Citations

Pneumonia tuberculosa: um estudo de 59 casos confirmados microbiologicamente

Moreira¹,

Fochesatto

Moreira

et al. 2011

J. bras. pneumol.

View full text Add to dashboard Cite

Objective: To study the clinical, epidemiological, radiographic and endoscopic features of individuals with tuberculous pneumonia. Methods: We evaluated 2,828 consecutive tuberculosis patients treated at a public health center between December of 2005 and February of 2007. Of those, 59 (2.1%) had pulmonary involvement consistent with fistula between a lymph node and a bronchus. Results: Of the 59 patients studied, 43 (73%) were between 20 and 50 years of age, 31 (53%) were male, and 28 (47%) were Black. The most common symptoms were cough (in 100%), fever (in 88%), expectoration (in 81%), and weight loss (in 40%). Comorbidities were reported in 35 cases (59%), the most common being HIV infection (in 20%) and diabetes (in 15%). On chest X-rays, consolidation was observed, predominantly in the upper lobes (in 68%). The diagnostic confirmation (identification of AFB) was made through the sputum smear microscopy in the majority of the cases and by bronchoscopy (BAL examination or bronchial biopsy) in the remainder. Bronchial lesions were clearly indicative or suggestive of fistula in three cases and five cases, respectively. Conclusions: Tuberculous pneumonia presents as acute respiratory infection, initiating with a dry cough that is followed by fever. Chest X-rays show alveolar consolidation. In most cases, tuberculous pneumonia was accompanied by at least one comorbid condition, the most common being HIV infection, and the etiological diagnosis was made through sputum smear microscopy for AFB. Bronchoscopy findings were indicative of bronchial fistula in eight cases (13%).Keywords: Mycobacterium tuberculosis; Pneumonia; Bronchial fistula; Lymph nodes. ResumoObjetivo: Estudar os aspectos clínicos, epidemiológicos, radiológicos e endoscópicos encontrados em indivíduos com pneumonia tuberculosa. Métodos: Entre dezembro de 2005 e fevereiro de 2007, foram estudados 2.828 pacientes com tuberculose que foram consecutivamente atendidos em uma unidade de saúde pública. Desses, 59 (2,1%) tiveram envolvimento pulmonar compatível com fístula entre um linfonodo e um brônquio. Resultados: Dos 59 pacientes estudados, 43 (73%) tinham entre 20 e 50 anos de idade, 31 (53%) eram do sexo masculino, e 28 (47%) eram negros. Os sintomas mais frequentes foram tosse (100%), febre (88%), expectoração (81%) e perda de peso (40%). Comorbidades foram registradas em 35 pacientes (59%), especialmente a infecção por HIV (20%) e diabetes (15%). Na radiografia de tórax, a consolidação predominou nos lobos superiores (em 68%). A confirmação diagnóstica (presença de BAAR) foi feita principalmente por baciloscopia direta do escarro, seguida por broncoscopia (LBA e biópsia brônquica). Lesões brônquicas claramente indicativas ou sugestivas de fístula foram identificadas em três casos e cinco casos, respectivamente. Conclusões: A pneumonia tuberculosa apresenta-se como uma infecção respiratória aguda, com tosse seca seguida por febre. A radiografia de tórax mostra consolidação alveolar. Na maioria dos casos, a pneumonia tuberculosa foi acompanh...

show abstract

Section: Resultscontrasting

confidence: 61%

Section: Discussionmentioning

confidence: 90%

mentioning

confidence: 99%

See 1 more Smart Citation

Pneumonia tuberculosa: um estudo de 59 casos confirmados microbiologicamente

Moreira¹,

Fochesatto

Moreira

et al. 2011

J. bras. pneumol.

View full text Add to dashboard Cite

show abstract

“…However, the use of other ototoxic drugs may lead to more frequent cochlear-vestibular toxicity which, in this particular case, could have been enhanced by the use of doxazosin mesylate and hydrochlorothiazide, both potentially ototoxic 13 . Non-steroidal anti-inflammatory drugs (NSAIDs) are related to reversible ototoxicity, with 1% to 3% incidence 17 .…”

Section: Discussionmentioning

confidence: 99%

First Report on Ototoxicity of Meglumine Antimoniate

Valete‐Rosalino

Araújo-Melo

Bezerra

et al. 2014

Rev. Inst. Med. trop. S. Paulo

View full text Add to dashboard Cite

Introduction: Pentavalent antimonials are the first drug of choice in the treatment of tegumentary leishmaniasis. Data on ototoxicity related with such drugs is scarcely available in literature, leading us to develop a study on cochleovestibular functions. Case Report: A case of a tegumentary leishmaniasis patient, a 78-year-old man who presented a substantial increase in auditory threshold with tinnitus and severe rotatory dizziness during the treatment with meglumine antimoniate, is reported. These symptoms worsened in two weeks after treatment was interrupted. Conclusion: Dizziness and tinnitus had already been related to meglumine antimoniate. However, this is the first well documented case of cochlear-vestibular toxicity related to meglumine antimoniate.

show abstract

“…The initial presentation was compatible with an advanced HIV infection phase complicated by disseminated tuberculosis and P. carinii pneumonia. Anemia, leukopenia, mild hepatosplenomegaly, and cachexia could be explained by HIV or by tuberculosis [2][3][4][5][6][7][8][9]. At that time, the patient did not present a low platelet count, a frequent observation in kala-azar [10].…”

Section: Discussionmentioning

confidence: 99%

Pneumocystis carinii pneumonia, pulmonary tuberculosis and visceral leishmaniasis in an adult HIV negative patient

Ac¹,

Mr²

2001

Braz J Infect Dis

View full text Add to dashboard Cite

This is a case report of a 29 year old male with pneumocystis pneumonia and tuberculosis, and who was initially suspected of having HIV infection, based on risk factor analyses, but was subsequently shown to be HIV negative. The patient arrived at the hospital with fever, cough, weight loss, loss of appetite, pallor, and arthralgia. In addition, he was jaundiced and had cervical lymphadenopathy and mild heptosplenomegaly. He had interstitial infiltrates of the lung, sputum smears positive for Mycobacterium tuberculosis and Pneumocystis carinii, and stool tests were positive for Strongyloides stercoralis and Schistosoma mansoni. He was diagnosed as having AIDS, and was treated for tuberculosis, pneumocystosis, and strongyloidiasis with a good response. The patient did not receive anti-retroviral therapy, pending outcome of the HIV tests. A month later, he was re-examined and found to have worsening hepatosplenomegaly, pancytopenia, fever, and continued weight loss. At this time, it was determined that his HIV ELISA antibody tests were negative. A bone marrow aspirate was done and revealed amastigotes of leishmania, and a bone marrow culture was positive for Leishmania species. He was treated with pentavalent antimony, 20 mg daily for 20 days, with complete remission of symptoms and weight gain. This case demonstrates that immunosuppression from leishmaniasis and tuberculosis may lead to pneumocystosis, and be misdiagnosed as HIV infection. The occurrence of opportunistic infections in severely ill patients without HIV must always be considered and alternate causes of immunosuppression sought

show abstract

Resultado do tratamento da tuberculose com estreptomicina, isoniazida e etambutol (esquema SHM)

Cited by 4 publications

References 5 publications

Pneumonia tuberculosa: um estudo de 59 casos confirmados microbiologicamente

Pneumonia tuberculosa: um estudo de 59 casos confirmados microbiologicamente

First Report on Ototoxicity of Meglumine Antimoniate

Pneumocystis carinii pneumonia, pulmonary tuberculosis and visceral leishmaniasis in an adult HIV negative patient

Contact Info

Product

Resources

About