2000
DOI: 10.1590/s0102-35862000000500002
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Fatores prognósticos em fibrose pulmonar idiopática

Abstract: Com o objetivo de avaliar quais fatores prognósticos são significativos na sobrevida de pacientes com fibrose pulmonar idiopática (FPI), foram estudados 117 casos com comprovação histológica da doença, internados no Pavilhão Pereira Filho entre 1970 e 1996. Todos os pacientes realizaram radiologia convencional de tórax, espirometria e preencheram um questionário padronizado no momento da internação. Foram também realizados medida da difusão (34 casos), capacidade pulmonar total (28), gasometria (106), lavado b… Show more

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Cited by 3 publications
(3 citation statements)
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“…25,26 In this study, the proportion of smokers and former smokers was lower than expected, as was the case in other series. 27,28 However, in the 15 patients aged under 60 years old, 80% had a history of cigarette smoking, so we can speculate that excluding ageing, smoking history could have been a significant risk factor for IPF in this sample. Twelve months was the median time between beginning of symptoms and diagnosis.…”
Section: Discussionmentioning
confidence: 80%
See 1 more Smart Citation
“…25,26 In this study, the proportion of smokers and former smokers was lower than expected, as was the case in other series. 27,28 However, in the 15 patients aged under 60 years old, 80% had a history of cigarette smoking, so we can speculate that excluding ageing, smoking history could have been a significant risk factor for IPF in this sample. Twelve months was the median time between beginning of symptoms and diagnosis.…”
Section: Discussionmentioning
confidence: 80%
“…However, in this sample there was no prognostic impact. There are some studies which show baseline PaO 2 at rest as a predictor of mortality, 8,27,43,46 although there are also some contradictory results. 44,47 Higher degrees of hypoxemia occur in more advanced stages of the disease but whether this can be considered as a prognostic factor or not, is yet to be established.…”
Section: Discussionmentioning
confidence: 99%
“…The mean survival of the individuals affected is approximately 3 years after diagnosis, and, among the treatment options available, none seems to substantially affect the progression of the disease. (2)(3)(4) The etiology of IPF is unknown. Various hypotheses have been investigated, and, among possible risk factors, smoking, environmental conditions, genetic predisposition, viral infections and chronic aspiration secondary to gastroesophageal reflux (GER) are considered.…”
Section: Introductionmentioning
confidence: 99%