Avaliação da aplicação do protocolo de triagem pré-natal para toxoplasmose em Belo Horizonte, Minas Gerais, Brasil: estudo transversal em puérperas de duas maternidades

Carellos, Ericka Viana Machado; Andrade, Gláucia Manzan Queiroz de; Aguiar, Regina Amélia Lopes Pessoa de

doi:10.1590/s0102-311x2008000200018

Cited by 34 publications

(28 citation statements)

References 24 publications

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“…These observations agree with previous studies that indicate a percentage of IgG anti-T. gondii antibodies in the Brazilian population (20,(23)(24)(25)(26)(27)(28)(29)(30).…”

Section: Discussionsupporting

confidence: 93%

Non-association between anti-Toxoplasma gondii antibodies and ABO blood group system

Rodrigues

Uezato

Vono

et al. 2011

J. Venom. Anim. Toxins incl. Trop. Dis

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Toxoplasma gondii infects humans through the gastrointestinal tract (GIT), which elicits humoral immune response with specific antibodies. The expression of the ABO blood group glycoconjugates also occurs in this same system and may influence the human susceptibility of infection by T. gondii. The aim of the present study was to investigate the association between ABO blood group phenotypes and the presence of anti-T. gondii antibodies. Data -including age, results of serology tests for T. gondii infection and ABO blood group phenotypes -were assembled from the medical records of 1,006 pregnant women attended in the Base Hospital of the Medical School of São José do Rio Preto, Brazil, between 2001 and 2004. The chi-square test was used to compare the results with the level of significance set at 5%. Of the studied cases, 64.1% (645/1006) and 35.9% (391/1006) presented respectively positive and negative serology tests for anti-T. gondii antibodies. The mean age of those who tested positive was higher than those with negative serology tests (p = 0.0004). The frequencies of ABO blood group phenotypes were similar in those with and without anti-T. gondii antibodies (p = 0.35). In conclusion, the ABO blood group system is not associated with the presence or absence of anti-T. gondii antibodies.

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“…These observations agree with previous studies that indicate a percentage of IgG anti-T. gondii antibodies in the Brazilian population (20,(23)(24)(25)(26)(27)(28)(29)(30).…”

Section: Discussionsupporting

confidence: 93%

Non-association between anti-Toxoplasma gondii antibodies and ABO blood group system

Rodrigues

Uezato

Vono

et al. 2011

J. Venom. Anim. Toxins incl. Trop. Dis

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“…6 In the present study more than 60% of the pregnant women tested positive for IgG anti-T. gondii antibodies, which is in agreement with other studies carried out in Brazil reporting seropositivity rates ranging from 22.8% to 71.5%. [7][8][9][10][11][12] Two recent studies performed in the northwest region of São Paulo State found rates similar to those reported in the current study. 5,13 Pregnant women at risk of congenital transmission of toxoplasmosis were younger than those without risk.…”

Section: Discussionsupporting

confidence: 91%

Seropositivity rates for toxoplasmosis, rubella, syphilis, cytomegalovirus, hepatitis and HIV among pregnant women receiving care at a public health service, São Paulo state, Brazil

Gonçalves¹,

Mattos²,

Spegiorin³

et al. 2010

Braz J Infect Dis

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Infectious and parasitic diseases affecting women during their reproductive age may result in vertical transmission. The aim of this study was to determine the seroprevalence for TORSCH among pregnant women receiving care at a university hospital. Records of 574 pregnant women who received medical attention from January 2006 to December 2007 were assessed. The mean age was 27.2 ± 6.5 years ranging from 13 to 44. The results of the immunodiagnostic tests were: 62.0% (345/556) for IgG and 3.4% (19/556) for IgM anti-T. gondii; 93.1% (433/465) for IgG and 0.6% (3/465) for IgM anti-rubella; 0.9% (5/561) for VDRL; 1.8% (10/554) for HBsAg; 0.7% (4/545) for anti-HCV and 2.1% (11/531) for HIV. In conclusion, the results of immunodiagnostic tests for the TORSCH panel among pregnant women attending a perinatal service of a university hospital are in agreement with those reported by previous studies and by governmental sources

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“…Some Brazilian states provide serological evaluation during prenatal care, but regardless, in most cases, these exams are performed too late to make a helpful diagnosis; furthermore, when the first exam is negative, there is no follow up in the subsequent months. Thus, there is no possibility of the early diagnosis of serological conversion and specific treatment during pregnancy 6 .…”

Section: Introductionmentioning

confidence: 99%

Incidence of congenital toxoplasmosis in the city of Belém, state of Pará, northern Brazil, determined by a neonatal screening program: preliminary results

Bichara

Canto

Tostes

et al. 2012

Rev. Soc. Bras. Med. Trop.

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Revista da Sociedade Brasileira de MedicinaABSTRAcT Introduction: The aim of this study was to determinate the incidence of congenital toxoplasmosis among a group of newborns (NBs) from Belém using neonatal screening. Methods: Among the 6,000 newborns referred for investigation of genetic and metabolic diseases, 1,000 were selected for screening for congenital toxoplasmosis by determining the amount of IgM in the eluates of blood collected on filter paper. Positive tests were confirmed using paired serology of the NB and his mother. Results: Out of the 1,000 NBs assessed, one had a positive screening result that was confirmed by paired serology. conclusions: The incidence of congenital toxoplasmosis in Belém was 10/10,000 live NBs.

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Avaliação da aplicação do protocolo de triagem pré-natal para toxoplasmose em Belo Horizonte, Minas Gerais, Brasil: estudo transversal em puérperas de duas maternidades

Cited by 34 publications

References 24 publications

Non-association between anti-Toxoplasma gondii antibodies and ABO blood group system

Non-association between anti-Toxoplasma gondii antibodies and ABO blood group system

Seropositivity rates for toxoplasmosis, rubella, syphilis, cytomegalovirus, hepatitis and HIV among pregnant women receiving care at a public health service, São Paulo state, Brazil

Incidence of congenital toxoplasmosis in the city of Belém, state of Pará, northern Brazil, determined by a neonatal screening program: preliminary results

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